underlying the efficacy of antibodies generated by a vaccine to treat oxycodone use disorder

labonet

labonet

SARS-CoV-2 Antibody persistence in COVID-19 convalescent plasma donors: Dependency on assay format and applicability to serosurveillance

Background: Antibody response length following SARS-CoV-2 an infection tends to be variable and depends upon severity of illness and methodology of detection.

Research design and strategies: COVID-19 convalescent plasma (CCP) from 18 donors was collected longitudinally for a most of 63 – 129 days following decision of signs. All of the samples had been initially screened by the Ortho Complete Ig take a look at to verify positivity and subsequently examined with 7 further direct sandwich or oblique binding assays (Ortho, Roche, Abbott, Broad Institute) directed in opposition to a wide range of antigen targets (S1, RBD, and NC), together with 2 neutralization assays (Broad Institute stay virus PRNT and Vitalant Analysis Institute Pseudovirus RVPN).

Outcomes: The direct detection assays (Ortho Complete Ig whole and Roche Complete Ig) confirmed growing ranges of antibodies over the time interval, in distinction to the oblique IgG assays that confirmed a decline. Neutralization assays additionally demonstrated declining responses; the VRI RVPN pseudovirus had a better fee of decline than the Broad PRNT stay virus assay.

Dialogue: These information present that along with variable particular person responses and associations with illness severity, the detection assay chosen contributes to the heterogeneous leads to antibody stability over time. Relying on the scope of the analysis, one assay could also be preferable over one other. For serosurveillance research, direct, double Ag-sandwich assays seem like your best option because of their stability; specifically, algorithms that embrace each S1 and NC primarily based assays can assist scale back the speed of false-positivity and discriminate between pure an infection and vaccine-derived seroreactivity.

Pharmacological mechanisms underlying the efficacy of antibodies generated by a vaccine to deal with oxycodone use dysfunction

Therapeutic vaccines supply a viable technique to deal with opioid use issues (OUD) complementary to present pharmacotherapies. The candidate Oxy(Gly)4-sKLH vaccine focusing on oxycodone displayed pre-clinical proof of efficacy, selectivity and security, and it’s now present process scientific analysis. To additional assist its implementation within the clinic, this examine examined vital in vivo neuropsychopharmacological properties of the Oxy(Gly)4-sKLH vaccine in rats. Whereas repeated immunizations with Oxy(Gly)4-sKLH had been obligatory to take care of the antibody response extra time, publicity to free oxycodone didn’t enhance oxycodone-specific antibody ranges in vaccinated rats, limiting issues of immune-related negative effects. Immunization with Oxy(Gly)4-sKLH achieved sustained antibody titers over a interval of 5 months following preliminary vaccination, supporting its potential for offering long-lasting safety.

In vivo research of selectivity confirmed that vaccination prevented oxycodone-induced however not methadone-induced antinociception, whereas nonetheless preserving the opioid antagonist naloxone’s pharmacological results. Vaccination didn’t intervene with fentanyl-induced antinociception or fentanyl distribution to the mind. These in vivo information affirm the beforehand reported in vitro selectivity profile of Oxy(Gly)4-sKLH. Vaccination prolonged oxycodone’s half-life as much as 25 hr in comparison with management. Whereas vaccination diminished the reinforcing efficacy of oxycodone in an intravenous self-administration mannequin, indicators of toxicity weren’t noticed. These rodent research affirm that energetic immunization with Oxy(Gly)4-sKLH induces extremely particular and long-lasting antibodies that are efficient in lowering the reinforcing results of oxycodone whereas preserving the efficacy of drugs used to deal with OUD and overdose.

labonet
labonet

anti- Galectin-1 antibody

FNab03315 100µg
EUR 658.5
Description: Antibody raised against Galectin-1

Human Galectin-1 (Gal-1) Antibody

30005-05111 150 ug
EUR 215

Human Galectin-1 (LGALS1)

1-CSB-EP012882HU
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
Description: Recombinant Human Galectin-1(LGALS1) expressed in E.coli

Human Galectin-1 (LGALS1)

1-CSB-EP012882HUb1
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
Description: Recombinant Human Galectin-1(LGALS1) expressed in E.coli

Human Galectin-3(Galectin-3)ELISA Kit

YLA0216HU-48T 48T Ask for price

Human Galectin-3(Galectin-3)ELISA Kit

YLA0216HU-96T 96T Ask for price

human anti-human galectin-3 mAb(2D)

E4A09H10-2D 50ug
EUR 275
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody

human anti-human galectin-3 mAb(5F)

E4A09H10-5F 50ug
EUR 275
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody

human anti-human galectin-3 mAb(A5)

E4A09H10-A5 50ug
EUR 275
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody

human anti-human galectin-3 mAb(G2)

E4A09H10-G2 50ug
EUR 275
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody

human anti-human galectin-3 mAb(H3)

E4A09H10-H3 50ug
EUR 275
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody

human anti-human galectin-3 mAb(T1)

E4A09H10-T1 50ug
EUR 275
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody

human anti-human galectin-3 mAb(N13)

E4A09H10-N13 50ug
EUR 275
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody

Anti Human Galectin-3 Polyclonal Antibody

KH040 each
EUR 778.8
Description: The Anti Human Galectin-3 Polyclonal Antibody is available in Europe and for worldwide shipping via Gentaur.

Recombinant Human Galectin-1

7-00427 10µg Ask for price

Recombinant Human Galectin-1

7-00428 50µg Ask for price

Recombinant Human Galectin-1

7-00429 1mg Ask for price

Recombinant Human Galectin-1

AP60482 100ug
EUR 449

Recombinant Human Galectin-1

HEOPP-0710 10ug Ask for price

RECOMBINANT HUMAN GALECTIN-1

GWB-BEA2B0 0.05 mg Ask for price

Recombinant Human Galectin-1

cyt-544-10g 10µg
EUR 60

Recombinant Human Galectin-1

cyt-544-1mg 1mg
EUR 1350

Recombinant Human Galectin-1

cyt-544-50g 50µg
EUR 145

Human Galectin 1 Protein

20-abx066725
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Human Galectin-1 Antibody Pair Set

ABPR-ZB244 5 plates, 15 plates Ask for price
Description: Quantitative determination of Human Galectin-1

Galectin-1, human recombinant

4648-10 each
EUR 170.4

Galectin-1, human recombinant

4648-1000 each
EUR 1977.6

Galectin-1, human recombinant

4648-50 each
EUR 314.4

Galectin-1 Human Recombinant

rAP-2252 Inquiry Ask for price

Human Galectin-1 ELISA Kit

EK5323 96 tests
EUR 599

Human Galectin-1 ELISA Kit

IHULGALS1KT each
EUR 702
Description: Human Galectin-1 ELISA Kit

Mouse Monoclonal anti-human Galectin-1

hAP-1228 50ug
EUR 400

Sheep Polyclonal anti-Human Galectin-1

hAP-5905 50ug
EUR 400

Anti-Mouse Galectin-1 Antibody

103-M223 100 µg
EUR 399
Description: The galectins constitute a large family of carbohydrate-binding proteins that function in many systems both intracellularly and following secretion. Galectins contain either one or two carbohydrate recognition domains (CRR) which mediate recognition of N-acetyl-lactosamine-containing glycoproteins. Some galectins exist in multiple isoforms due to alternative splicing. Individual galectins differ in their tissue distribution and in their carbohydrate-binding specificities.

Human Galectin-1 (LEG1) Protein

abx690252-100g 100 µg
EUR 837.5

Human Galectin-1 (LEG1) Protein

abx690252-20g 20 µg
EUR 350

Human Galectin 1 (GAL1) ELISA

KT-15605 96 tests
EUR 952

Human Galectin-1 (LGALS1) Protein

abx670211-50ug 50 ug
EUR 661.2

Human Galectin 1 ELISA kit

E01A4669 96T
EUR 700
Description: ELISA

Human Galectin 1 ELISA kit

E01G0038-192T 192 tests
EUR 1524
Description: A sandwich ELISA for quantitative measurement of Human Galectin 1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Galectin 1 ELISA kit

E01G0038-48 1 plate of 48 wells
EUR 624
Description: A sandwich ELISA for quantitative measurement of Human Galectin 1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Galectin 1 ELISA kit

E01G0038-96 1 plate of 96 wells
EUR 822
Description: A sandwich ELISA for quantitative measurement of Human Galectin 1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Galectin 1 ELISA Kit

IHUGAL1KT each
EUR 667
Description: Human Galectin 1 ELISA Kit

Galectin-10, Human

E34M155H 5 μg
EUR 155

Galectin-12, Human

E34M156H 5 μg
EUR 155

Galectin-13, Human

E34M157H 5 μg
EUR 155

Galectin-14, Human

E34M158H 5 μg
EUR 155

Galectin-16, Human

E34M159H 5 μg
EUR 155

Galectin-2, Human

E34M149H 5 μg
EUR 155

Galectin-3, Human

E34M150H 5 μg
EUR 155

Galectin-4, Human

E34M151H 5 μg
EUR 155

Galectin-7, Human

E34M152H 5 μg
EUR 155

Galectin-8, Human

E34M153H 5 μg
EUR 155

Galectin-9, Human

E34M154H 5 μg
EUR 155

Galectin-3 Human

GWB-1FDCC0 0.05 mg Ask for price

Anti-Human Galectin-3 Antibody

101-M424 100 µg
EUR 399
Description: The galectins constitute a large family of carbohydrate-binding proteins that function in many systems both intracellularly and following secretion. Galectins contain either one or two carbohydrate recognition domains (CRR) which mediate recognition of N-acetyl-lactosamine-containing glycoproteins. Some galectins exist in multiple isoforms due to alternative splicing. Individual galectins differ in their tissue distribution and in their carbohydrate-binding specificities.

Anti-Human Galectin-4 Antibody

101-M425 100 µg
EUR 399
Description: Galectin-4 is a member of the subfamily of galectins composed of two carbohydrate recognition domains having similar peptide chains. The galectins are a family of beta-galactoside-binding proteins having a role in modulating cell-cell and cell-matrix interactions, which inhibits chronic inflammations, GVHD, and allergic responses. LGALS4 expression is limited to small intestine, colon, and rectum, and it is underexpressed in colorectal cancer. LGALS4 binds as an endogenous ligand to glycosphingolipids having 3-O-sulfated Gal residues and bind as well to cholesterol-3-sulfate. LGALS4 takes part in cell adhesion. LGALS4 plays a role in crosslinking the lateral cell membranes of the surface-lining epithelial cells, thus supporting epithelial integrity against mechanical stress exerted by the bowel lume.

Anti-Human Galectin-8 Antibody

101-M427 100 µg
EUR 399
Description: LGALS8 is a prostate-specific antigen that is solely overexpressed in malignant tumors and thus is a supplementary specific identifier of malignancies. LGALS8 is part of the galectin gene family which facilitates both cell-cell and cell matrix interactions in a method parallel to the selectin subgroup of C-type lectins.

Anti-Human Galectin-3 Antibody

101-M747 100 µg
EUR 399
Description: The galectins constitute a large family of carbohydrate-binding proteins that function in many systems both intracellularly and following secretion. Galectins contain either one or two carbohydrate recognition domains (CRR) which mediate recognition of N-acetyl-lactosamine-containing glycoproteins. Some galectins exist in multiple isoforms due to alternative splicing. Individual galectins differ in their tissue distribution and in their carbohydrate-binding specificities.

Anti-Human Galectin-7 Antibody

101-M748 100 µg
EUR 399
Description: Galectin-7 is a protein that in humans is encoded by the LGALS7 gene. The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell–cell and cell–matrix interactions. Differential and in situ hybridizations indicate that this lectin is specifically expressed in keratinocytes. It is expressed at all stages of epidermal differentiation (i.e., in basal and supra-basal layers). It is moderately repressed by retinoic acid. The protein was found mainly in stratified squamous epithelium. The antigen localized to basal keratinocytes, although it was also found, albeit at lower levels, in the supra-basal layers where it concentrated to areas of cell-to-cell contact. The cellular localization and it’s striking down-regulation in cultured keratinocytes imply a role in cell–cell and/or cell–matrix interactions necessary for normal growth control.

Anti-Human Galectin-3 Antibody

102-P228 100 µg
EUR 245.7
Description: The galectins constitute a large family of carbohydrate-binding proteins that function in many systems both intracellularly and following secretion. Galectins contain either one or two carbohydrate recognition domains (CRR) which mediate recognition of N-acetyl-lactosamine-containing glycoproteins. Some galectins exist in multiple isoforms due to alternative splicing. Individual galectins differ in their tissue distribution and in their carbohydrate-binding specificities.

anti-human Galectin-3 antibody

10-2887 250 ug
EUR 410
Description: Purified anti-human Galectin-3 antibody

Anti-human Galectin-3 antibody

STJ15100163 250 µg
EUR 403.2
Description: This monoclonal antibody is for studies of antigen expression in cells and tissue sections using immunocytochemistry and immunoprecipitation

Recombinant Human Galectin-1(LGALS1)

AP70493 1mg
EUR 1978

Recombinant Human Galectin-1 (LGALS1)

CSB-EP012882HU 1598 mg Ask for price

Recombinant Human Galectin-1 (LGALS1)

CSB-EP012882HUb1 1599 mg Ask for price

Recombinant Human Galectin-1 (LGALS1)

Z101845 15 µg
EUR 105
Description: Galectin-1 is a member of the galectin family, and binds B-galactosidase moieties on glycoproteins or glycolipids. Galectins are primarily involved in modulation of cell-cell and cell-matrix interactions. Galectin-1 acts as a negative regulator of immunity, promoting immune suppression and lessening the inflammatory response. Galectin-1 binds CD45, CD3 and CD4, resulting in the inhibition of CD45 phosphatase dependant dephosphorylation of lyn kinase, as well as a number of other immune related receptors. Due to its function as a negative regulator of the immune response, and role inducing apoptosis in activated Th1 and Th17 cells, it is commonly found upregulated around malignant tumours. It has also been implicated as having a role in the development of immune tolerance during pregnancy, and is highly expressed at the maternal-fetal interface. As a dimer it down-regulates neutrophils by inducing exposure of phosphatidylserine, thereby marking the cell for apoptosis. It shares approximately 88% and 90% sequence similarity with mouse and rat galectin-1, respectively. Recombinant Human Galectin-1 is a 14.9kDa protein.

Recombinant Human Galectin-1 (LGALS1)

Z101847 100 µg
EUR 270
Description: Galectin-1 is a member of the galectin family, and binds B-galactosidase moieties on glycoproteins or glycolipids. Galectins are primarily involved in modulation of cell-cell and cell-matrix interactions. Galectin-1 acts as a negative regulator of immunity, promoting immune suppression and lessening the inflammatory response. Galectin-1 binds CD45, CD3 and CD4, resulting in the inhibition of CD45 phosphatase dependant dephosphorylation of lyn kinase, as well as a number of other immune related receptors. Due to its function as a negative regulator of the immune response, and role inducing apoptosis in activated Th1 and Th17 cells, it is commonly found upregulated around malignant tumours. It has also been implicated as having a role in the development of immune tolerance during pregnancy, and is highly expressed at the maternal-fetal interface. As a dimer it down-regulates neutrophils by inducing exposure of phosphatidylserine, thereby marking the cell for apoptosis. It shares approximately 88% and 90% sequence similarity with mouse and rat galectin-1, respectively. Recombinant Human Galectin-1 is a 14.9kDa protein.

Recombinant Human Galectin-1 (LGALS1)

Z101849 1.0 mg
EUR 1135
Description: Galectin-1 is a member of the galectin family, and binds B-galactosidase moieties on glycoproteins or glycolipids. Galectins are primarily involved in modulation of cell-cell and cell-matrix interactions. Galectin-1 acts as a negative regulator of immunity, promoting immune suppression and lessening the inflammatory response. Galectin-1 binds CD45, CD3 and CD4, resulting in the inhibition of CD45 phosphatase dependant dephosphorylation of lyn kinase, as well as a number of other immune related receptors. Due to its function as a negative regulator of the immune response, and role inducing apoptosis in activated Th1 and Th17 cells, it is commonly found upregulated around malignant tumours. It has also been implicated as having a role in the development of immune tolerance during pregnancy, and is highly expressed at the maternal-fetal interface. As a dimer it down-regulates neutrophils by inducing exposure of phosphatidylserine, thereby marking the cell for apoptosis. It shares approximately 88% and 90% sequence similarity with mouse and rat galectin-1, respectively. Recombinant Human Galectin-1 is a 14.9kDa protein.

Human Galectin-1 ELISA ELISA Kit

E16HE0311 96T
EUR 1000

Human Galectin-1 Recombinant Protein

100-175 50 µg
EUR 196.35
Description: Lectins, of either plant or animal origin, are carbohydrate binding proteins that interact with glycoprotein and glycolipids on the surface of animal cells. The Galectins are lectins that recognize and interact with β-galactoside moieties. Galectin-1 is an animal lectin that has been shown to interact with CD3, CD4, and CD45. It induces apoptosis of activated T-cells and T-leukemia cell lines and inhibits the protein phosphatase activity of CD45. Recombinant human Galectin-1 is a 14.5 kDa protein containing 134 amino acid residues.

Human Galectin-1 Recombinant Protein

100-175S 10 µg
EUR 92.4
Description: Lectins, of either plant or animal origin, are carbohydrate binding proteins that interact with glycoprotein and glycolipids on the surface of animal cells. The Galectins are lectins that recognize and interact with β-galactoside moieties. Galectin-1 is an animal lectin that has been shown to interact with CD3, CD4, and CD45. It induces apoptosis of activated T-cells and T-leukemia cell lines and inhibits the protein phosphatase activity of CD45. Recombinant human Galectin-1 is a 14.5 kDa protein containing 134 amino acid residues.

Human Galectin-1 Recombinant Protein

400-015 50 µg
EUR 126
Description: Lectins, of either plant or animal origin, are carbohydrate binding proteins that interact with glycoprotein and glycolipids on the surface of animal cells. The Galectins are lectins that recognize and interact with beta-galactoside moieties. Galectin-1 is an animal lectin that has been shown to interact with CD3, CD4, and CD45. It induces apoptosis of activated T-cells and T-leukemia cell lines and inhibits the protein phosphatase activity of CD45. Recombinant human Galectin-1 is a 14.5 kDa protein containing 134 amino acid residues.

Recombinant Human Galectin-1 Protein

E40KMP1041 20ug
EUR 495

Recombinant Human Galectin-1 Protein

PROTP09382-1 50ug
EUR 380.4
Description: Lectins, of either plant or animal origin, are carbohydrate binding proteins that interact with glycoprotein and glycolipids on the surface of animal cells. The Galectins are lectins that recognize and interact with β-galactoside moieties. Galectin-1 is an animal lectin that has been shown to interact with CD3, CD4, and CD45. It induces apoptosis of activated T-cells and T-leukemia cell lines and inhibits the protein phosphatase activity of CD45. Recombinant human Galectin-1 is a 14.5 kDa protein containing 134 amino acid residues.

Human Galectin 10 Antibody

32652-05111 150 ug
EUR 215

Human Galectin 8 Antibody

33159-05111 150 ug
EUR 215

Human Galectin 2 Antibody

33165-05111 150 ug
EUR 215

Human Galectin 13 Antibody

33175-05111 150 ug
EUR 215

Human Galectin 1 (LGALS1) Protein

abx066725-100g 100 µg
EUR 512.5

Human Galectin 1 (LGALS1) Protein

abx066725-10g 10 µg
EUR 212.5

Human Galectin 1 (LGALS1) Protein

abx066725-50g 50 µg
EUR 362.5

Human Galectin 1 (LGALS1) Protein

abx670211-100g 100 µg
EUR 450

Human Galectin-1(LGALS1) ELISA kit

E01A4871 96T
EUR 700
Description: ELISA

Human Galectin-1(LGALS1) ELISA kit

E01G0448-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Human Galectin-1(LGALS1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Galectin-1(LGALS1) ELISA kit

E01G0448-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Human Galectin-1(LGALS1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Galectin-1(LGALS1) ELISA kit

E01G0448-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Human Galectin-1(LGALS1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Galectin-1(LGALS1) ELISA kit

EKC33776-48T 48T
EUR 535.99

Human Galectin-1(LGALS1) ELISA kit

EKC33776-5x96T 5x96T
EUR 3637.08

Human Galectin-1(LGALS1) ELISA kit

EKC33776-96T 96T
EUR 765.7

Human Galectin-1(LGALS1) Elisa Kit

EK712878 96 Wells
EUR 0.3

Human Galectin-1 (LGALS1) ELISA Kit

AE35699HU-48Tests 48 Tests
EUR 325
Description: Human (Homo sapiens)

Human Galectin-1 (LGALS1) ELISA Kit

AE35699HU-96Tests 96 Tests
EUR 610
Description: Human (Homo sapiens)

Human Galectin-1(LGALS1) ELISA kit

CSB-EL012882HU-24T 1 plate of 24 wells
EUR 198
Description: Quantitativesandwich ELISA kit for measuring Human Galectin-1 (LGALS1) in samples from serum, plasma, tissue homogenates, cell lysates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Human Galectin-1(LGALS1) ELISA kit

1-CSB-EL012882HU
  • Ask for price
  • Ask for price
  • Ask for price
  • 1 plate of 96 wells
  • 10 plates of 96 wells each
  • 5 plates of 96 wells each
Description: Quantitativesandwich ELISA kit for measuring Human Galectin-1(LGALS1) in samples from serum, plasma, tissue homogenates, cell lysates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Human Galectin 1 (GAL1) CLIA Kit

20-abx190336
  • Ask for price
  • Ask for price
  • Ask for price
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Human Galectin 1 (GAL1) CLIA Kit

abx196676-96tests 96 tests
EUR 990

Human Galectin 1 (GAL1) CLIA Kit

EKN51025-48T 48T
EUR 414.89

Human Galectin 1 (GAL1) CLIA Kit

EKN51025-5x96T 5x96T
EUR 2815.33

Human Galectin 1 (GAL1) CLIA Kit

EKN51025-96T 96T
EUR 592.7

Human Galectin 1 (GAL1) CLIA Kit

EKU09914-48T 48T
EUR 666.82

Human Galectin 1 (GAL1) CLIA Kit

EKU09914-5x96T 5x96T
EUR 4524.85

Human Galectin 1 (GAL1) CLIA Kit

EKU09914-96T 96T
EUR 952.6

Human Galectin 1 (GAL1)CLIA Kit

SCA321Hu-10x96wellstestplate 10x96-wells test plate
EUR 6777.36
Description: This is Double-antibody Sandwich Chemiluminescent immunoassay for detection of Human Galectin 1 (GAL1) in serum, plasma and other biological fluids.

Human Galectin 1 (GAL1)CLIA Kit

SCA321Hu-1x48wellstestplate 1x48-wells test plate
EUR 663.31
Description: This is Double-antibody Sandwich Chemiluminescent immunoassay for detection of Human Galectin 1 (GAL1) in serum, plasma and other biological fluids.

Human Galectin 1 (GAL1)CLIA Kit

SCA321Hu-1x96wellstestplate 1x96-wells test plate
EUR 896.16
Description: This is Double-antibody Sandwich Chemiluminescent immunoassay for detection of Human Galectin 1 (GAL1) in serum, plasma and other biological fluids.

Human Galectin 1 (GAL1)CLIA Kit

SCA321Hu-5x96wellstestplate 5x96-wells test plate
EUR 3672.72
Description: This is Double-antibody Sandwich Chemiluminescent immunoassay for detection of Human Galectin 1 (GAL1) in serum, plasma and other biological fluids.

Human Galectin 1 (GAL1) CLIA Kit

4-SCA321Hu
  • Ask for price
  • Ask for price
  • Ask for price
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
Description: Double-antibody Sandwich chemiluminescent immunoassay for detection of Human Galectin 1 (GAL1)Serum, plasma and other biological fluids

Human Galectin-1 (Gal-1) Antibody (Biotin Conjugate)

30005-05121 150 ug
EUR 315

Human GAL1 -Galectin 1 - CLIA Kit

E-CL-H0704-24Tests 24 Tests
EUR 180
Description: Sandwich

Human GAL1 -Galectin 1 - CLIA Kit

E-CL-H0704-48Tests 48 Tests
EUR 546
Description: Sandwich

Human GAL1 -Galectin 1 - CLIA Kit

E-CL-H0704-96Tests 96 Tests
EUR 682
Description: Sandwich

Human GAL1 -Galectin 1 - CLIA Kit

E-CL-H0704-96Tests10 96 Tests *10
EUR 6820
Description: Sandwich

Human GAL1 -Galectin 1 - CLIA Kit

E-CL-H0704-96Tests5 96 Tests *5
EUR 3410
Description: Sandwich

Galectin-1

AP89417 1mg
EUR 2640

Galectin-1

AP84615 1mg
EUR 2640

Galectin-1

AP84729 1mg
EUR 2640

Galectin-1

AP84945 1mg
EUR 2640

Galectin-1

AP85083 1mg
EUR 2640

Human Galectin 1 (GAL1) ELISA kit

201-12-3227 96 tests
EUR 528
Description: A quantitative ELISA kit for measuring Human in samples from biological fluids.

Human Galectin 1 (GAL1) ELISA Kit

DLR-GAL1-Hu 96T
EUR 422
Description: serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Human Galectin 1 (GAL1) ELISA Kit

DLR-GAL1-Hu-48T 48T
EUR 574.8
Description: A sandwich quantitative ELISA assay kit for detection of Human Galectin 1 (GAL1) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Human Galectin 1 (GAL1) ELISA Kit

DLR-GAL1-Hu-96T 96T
EUR 745.2
Description: A sandwich quantitative ELISA assay kit for detection of Human Galectin 1 (GAL1) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Human Galectin 1 (GAL1) ELISA Kit

EKL57418-5x96T 5x96T
EUR 3452.78

Human Galectin 1 (GAL1) ELISA Kit

EKL57418-96T 96T
EUR 726.9

Human Galectin 1 (GAL1) ELISA Kit

EKU11884-48T 48T
EUR 474.74

Human Galectin 1 (GAL1) ELISA Kit

EKU11884-5x96T 5x96T
EUR 3221.45

Myelin Oligodendrocyte Glycoprotein-antibody-associated Dysfunction Presenting with Corticomeningeal Encephalitis previous to the Onset of Optic Neuritis

We herein report a case of myelin oligodendrocyte glycoprotein-antibody-associated dysfunction (MOG-AD) presenting with corticomeningeal encephalitis. The affected person exhibited oral ulceration, a light impairment of consciousness, fever, nausea, nuchal rigidity, positivity for human leukocyte antigen sort B51, and neutrophil-dominant pleocytosis and interleukin-6 stage in cerebrospinal fluid (CSF). Magnetic resonance imaging (MRI) revealed a proper temporal lesion with leptomeningeal gadolinium enhancement.

The preliminary analysis was neuro-Behçet’s illness presenting with meningoencephalitis; nevertheless, a cell-based assay detected anti-MOG antibody within the serum and CSF and the affected person additionally skilled bilateral optic neuritis. After administering steroid remedy, his neurologic signs and CSF abnormalities improved together with the disappearance of gadolinium enhancement and the lesion on MRI. This case means that MOG-AD could current with corticomeningeal encephalitis previous to the onset of optic neuritis.

Excessive antibody ranges in opposition to human herpesvirus-6A work together with way of life elements in a number of sclerosis improvement

 

Background: An infection with human herpesvirus 6A (HHV-6A) has been steered to extend a number of sclerosis (MS) threat. Nonetheless, potential interactions between HHV-6A and environmental/way of life threat elements for MS haven’t beforehand been studied.

Strategies: We used two Swedish population-based case-control research comprising 5993 circumstances and 5995 controls. Utilizing logistic regression fashions, topics with completely different HHV-6A antibody ranges, environmental exposures, and way of life habits had been in contrast concerning MS threat, by calculating odds ratios (ORs) with 95% confidence intervals (CIs). Potential interactions between excessive HHV-6A antibody ranges and customary environmental exposures and way of life elements had been evaluated on the additive scale.

Outcomes: Excessive HHV-6A antibody ranges had been related to elevated threat of creating MS (OR = 1.5, 95% CI = 1.4-1.6). Concerning MS threat, important interactions had been noticed between excessive HHV-6A antibody ranges and each smoking (attributable proportion (AP) = 0.2, 95% CI = 0.1-0.3), low ultraviolet radiation (UVR) publicity (AP = 0.3, 95% CI = 0.1-0.4), and low vitamin D ranges (AP = 0.3, 95% CI = 0.0-0.6).

Conclusion: Excessive HHV-6A antibody ranges are related to elevated MS threat and act synergistically with widespread environmental/way of life threat elements for MS. Additional analysis is required to research potential mechanisms underlying the interactions introduced on this examine.

Immune subtraction for improved decision in serum protein immunofixation electrophoresis and antibody isotype willpower in a affected person with autoantibody

 

Heavy chain isotypes of low stage monoclonal immunoglobulins are generally obscured in serum immunofixation electrophoresis (SIFE) by a heavy background of polyclonal immunoglobulins. Nonetheless, correct willpower of the heavy chain isotype is important for a whole analysis, as isotype willpower of autoantibodies could have relevance in figuring out therapeutic procedures. Immune subtraction (IS) was employed in a affected person with neuropathy and GD1a autoantibody. IS allowed identification of the cognate heavy chain associated to a lambda mild chain restriction famous on preliminary SIFE in addition to isotype willpower of the autoantibody. Antisera particular to particular person heavy and lightweight chains had been used for depletion of particular immunoglobulin varieties. Depletion of kappa mild chain related immunoglobulins allowed unequivocal willpower of the isotype of lambda mild chain-associated low stage monoclonal band to be IgG Lambda. Selective depletion of kappa, lambda, gamma and mu heavy chain immunoglobulins was employed to decide IgG Kappa isotype of the auto-antibody.

Related Post

Leave a Reply

Your email address will not be published. Required fields are marked *