underlying the efficacy of antibodies generated by a vaccine to treat oxycodone use disorder

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labonet

SARS-CoV-2 Antibody persistence in COVID-19 convalescent plasma donors: Dependency on assay format and applicability to serosurveillance

Background: Antibody response length following SARS-CoV-2 an infection tends to be variable and depends upon severity of illness and methodology of detection.

Research design and strategies: COVID-19 convalescent plasma (CCP) from 18 donors was collected longitudinally for a most of 63 – 129 days following decision of signs. All of the samples had been initially screened by the Ortho Complete Ig take a look at to verify positivity and subsequently examined with 7 further direct sandwich or oblique binding assays (Ortho, Roche, Abbott, Broad Institute) directed in opposition to a wide range of antigen targets (S1, RBD, and NC), together with 2 neutralization assays (Broad Institute stay virus PRNT and Vitalant Analysis Institute Pseudovirus RVPN).

Outcomes: The direct detection assays (Ortho Complete Ig whole and Roche Complete Ig) confirmed growing ranges of antibodies over the time interval, in distinction to the oblique IgG assays that confirmed a decline. Neutralization assays additionally demonstrated declining responses; the VRI RVPN pseudovirus had a better fee of decline than the Broad PRNT stay virus assay.

Dialogue: These information present that along with variable particular person responses and associations with illness severity, the detection assay chosen contributes to the heterogeneous leads to antibody stability over time. Relying on the scope of the analysis, one assay could also be preferable over one other. For serosurveillance research, direct, double Ag-sandwich assays seem like your best option because of their stability; specifically, algorithms that embrace each S1 and NC primarily based assays can assist scale back the speed of false-positivity and discriminate between pure an infection and vaccine-derived seroreactivity.

Pharmacological mechanisms underlying the efficacy of antibodies generated by a vaccine to deal with oxycodone use dysfunction

Therapeutic vaccines supply a viable technique to deal with opioid use issues (OUD) complementary to present pharmacotherapies. The candidate Oxy(Gly)4-sKLH vaccine focusing on oxycodone displayed pre-clinical proof of efficacy, selectivity and security, and it’s now present process scientific analysis. To additional assist its implementation within the clinic, this examine examined vital in vivo neuropsychopharmacological properties of the Oxy(Gly)4-sKLH vaccine in rats. Whereas repeated immunizations with Oxy(Gly)4-sKLH had been obligatory to take care of the antibody response extra time, publicity to free oxycodone didn’t enhance oxycodone-specific antibody ranges in vaccinated rats, limiting issues of immune-related negative effects. Immunization with Oxy(Gly)4-sKLH achieved sustained antibody titers over a interval of 5 months following preliminary vaccination, supporting its potential for offering long-lasting safety.

In vivo research of selectivity confirmed that vaccination prevented oxycodone-induced however not methadone-induced antinociception, whereas nonetheless preserving the opioid antagonist naloxone’s pharmacological results. Vaccination didn’t intervene with fentanyl-induced antinociception or fentanyl distribution to the mind. These in vivo information affirm the beforehand reported in vitro selectivity profile of Oxy(Gly)4-sKLH. Vaccination prolonged oxycodone’s half-life as much as 25 hr in comparison with management. Whereas vaccination diminished the reinforcing efficacy of oxycodone in an intravenous self-administration mannequin, indicators of toxicity weren’t noticed. These rodent research affirm that energetic immunization with Oxy(Gly)4-sKLH induces extremely particular and long-lasting antibodies that are efficient in lowering the reinforcing results of oxycodone whereas preserving the efficacy of drugs used to deal with OUD and overdose.

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labonet

Recombinant Human Galectin-1

7-00429 1mg Ask for price

Recombinant Human Galectin-1

HEOPP-0710 10ug Ask for price

Human Galectin 1 Protein

20-abx066725
  • EUR 744.00
  • EUR 326.40
  • EUR 2230.80
  • EUR 878.40
  • EUR 543.60
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Galectin-1, human recombinant

4648-10 each
EUR 170.4

Galectin-1, human recombinant

4648-1000 each
EUR 1977.6

Galectin-1, human recombinant

4648-50 each
EUR 314.4

Human Galectin 1 ELISA kit

E01G0038-192T 192 tests
EUR 1524
Description: A sandwich ELISA for quantitative measurement of Human Galectin 1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Galectin 1 ELISA kit

E01G0038-48 1 plate of 48 wells
EUR 624
Description: A sandwich ELISA for quantitative measurement of Human Galectin 1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Galectin 1 ELISA kit

E01G0038-96 1 plate of 96 wells
EUR 822
Description: A sandwich ELISA for quantitative measurement of Human Galectin 1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Galectin-1 (LGALS1) Protein

abx670211-50ug 50 ug
EUR 661.2

Anti-human Galectin-3 antibody

STJ15100163 250 µg
EUR 403.2
Description: This monoclonal antibody is for studies of antigen expression in cells and tissue sections using immunocytochemistry and immunoprecipitation

ELISA kit for Human Galectin-1

EK5323 96 tests
EUR 663.6
Description: Enzyme-linked immunosorbent assay kit for quantification of Human Galectin-1 in samples from serum, plasma, tissue homogenates and other biological fluids.

Galectin-1 Antibody

3596-100 each
EUR 379.2

Galectin-1 Antibody

3596-30T each
EUR 175.2

Galectin-1 Antibody

R34524-100UG 100 ug
EUR 339.15
Description: Additional name(s) for this target protein: Lectin, galactose binding, soluble 1; Lgals1

Galectin-1 Antibody

R34565-100UG 100 ug
EUR 339.15
Description: Additional name(s) for this target protein: Lgals1

anti- Galectin-3 antibody

FNab03316 100µg
EUR 606.3
Description: Antibody raised against Galectin-3

anti- Galectin-3 antibody

FNab03317 100µg
EUR 658.5
Description: Antibody raised against Galectin-3

anti- Galectin-7 antibody

FNab03318 100µg
EUR 606.3
Description: Antibody raised against Galectin-7

Human Galectin 8 Antibody

33159-05111 150 ug
EUR 313.2

Human Galectin 2 Antibody

33165-05111 150 ug
EUR 313.2

Human Galectin 13 Antibody

33175-05111 150 ug
EUR 313.2

Human Galectin 10 Antibody

32652-05111 150 ug
EUR 313.2

Recombinant Human Galectin-1 Protein

PROTP09382-1 50ug
EUR 380.4
Description: Lectins, of either plant or animal origin, are carbohydrate binding proteins that interact with glycoprotein and glycolipids on the surface of animal cells. The Galectins are lectins that recognize and interact with β-galactoside moieties. Galectin-1 is an animal lectin that has been shown to interact with CD3, CD4, and CD45. It induces apoptosis of activated T-cells and T-leukemia cell lines and inhibits the protein phosphatase activity of CD45. Recombinant human Galectin-1 is a 14.5 kDa protein containing 134 amino acid residues.

Recombinant Human Galectin-1 Protein

RP00007 20 μg
EUR 208.8

Human Galectin 1 (GAL1) CLIA Kit

20-abx190336
  • EUR 9493.20
  • EUR 5058.00
  • EUR 1167.60
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Human Galectin 1 (GAL1) CLIA Kit

abx196676-96tests 96 tests
EUR 990

Human Galectin 1 (GAL1)CLIA Kit

SCA321Hu-10x96wellstestplate 10x96-wells test plate
EUR 6777.36
Description: This is Double-antibody Sandwich Chemiluminescent immunoassay for detection of Human Galectin 1 (GAL1) in serum, plasma and other biological fluids.

Human Galectin 1 (GAL1)CLIA Kit

SCA321Hu-1x48wellstestplate 1x48-wells test plate
EUR 663.31
Description: This is Double-antibody Sandwich Chemiluminescent immunoassay for detection of Human Galectin 1 (GAL1) in serum, plasma and other biological fluids.

Human Galectin 1 (GAL1)CLIA Kit

SCA321Hu-1x96wellstestplate 1x96-wells test plate
EUR 896.16
Description: This is Double-antibody Sandwich Chemiluminescent immunoassay for detection of Human Galectin 1 (GAL1) in serum, plasma and other biological fluids.

Human Galectin 1 (GAL1)CLIA Kit

SCA321Hu-5x96wellstestplate 5x96-wells test plate
EUR 3672.72
Description: This is Double-antibody Sandwich Chemiluminescent immunoassay for detection of Human Galectin 1 (GAL1) in serum, plasma and other biological fluids.

Human Galectin 1 (GAL1) CLIA Kit

4-SCA321Hu
  • EUR 6837.60
  • EUR 3673.20
  • EUR 896.40
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
Description: Double-antibody Sandwich chemiluminescent immunoassay for detection of Human Galectin 1 (GAL1)Serum, plasma and other biological fluids

Human Galectin-1(LGALS1) ELISA kit

CSB-EL012882HU-24T 1 plate of 24 wells
EUR 198
Description: Quantitativesandwich ELISA kit for measuring Human Galectin-1 (LGALS1) in samples from serum, plasma, tissue homogenates, cell lysates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Human Galectin-1(LGALS1) ELISA kit

1-CSB-EL012882HU
  • EUR 964.80
  • EUR 6118.80
  • EUR 3244.80
  • 1 plate of 96 wells
  • 10 plates of 96 wells each
  • 5 plates of 96 wells each
Description: Quantitativesandwich ELISA kit for measuring Human Galectin-1(LGALS1) in samples from serum, plasma, tissue homogenates, cell lysates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Human Galectin-1(LGALS1) ELISA kit

E01G0448-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Human Galectin-1(LGALS1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Galectin-1(LGALS1) ELISA kit

E01G0448-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Human Galectin-1(LGALS1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Galectin-1(LGALS1) ELISA kit

E01G0448-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Human Galectin-1(LGALS1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Galectin-1 (Gal-1) Antibody (Biotin Conjugate)

30005-05121 150 ug
EUR 442.8

Human Galectin 1 (GAL1) ELISA kit

201-12-3227 96 tests
EUR 528
Description: A quantitative ELISA kit for measuring Human in samples from biological fluids.

Human Galectin 1 (GAL1) ELISA Kit

DLR-GAL1-Hu-48T 48T
EUR 574.8
Description: A sandwich quantitative ELISA assay kit for detection of Human Galectin 1 (GAL1) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Human Galectin 1 (GAL1) ELISA Kit

DLR-GAL1-Hu-96T 96T
EUR 745.2
Description: A sandwich quantitative ELISA assay kit for detection of Human Galectin 1 (GAL1) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Human Galectin 1 ELISA Kit (GAL1)

RK01436 96 Tests
EUR 625.2

Human Galectin 1 (GAL1) ELISA Kit

RDR-GAL1-Hu-48Tests 48 Tests
EUR 600

Human Galectin 1 (GAL1) ELISA Kit

RDR-GAL1-Hu-96Tests 96 Tests
EUR 830.4

Human Galectin 1(GAL1)ELISA Kit

QY-E04196 96T
EUR 433.2

Human Galectin 1 (GAL1) ELISA Kit

RD-GAL1-Hu-48Tests 48 Tests
EUR 573.6

Human Galectin 1 (GAL1) ELISA Kit

RD-GAL1-Hu-96Tests 96 Tests
EUR 794.4

Human Galectin 1 (GAL1) ELISA Kit

SEA321Hu-10x96wellstestplate 10x96-wells test plate
EUR 4091.29
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Galectin 1 (GAL1) in serum, plasma, tissue homogenates and other biological fluids.

Human Galectin 1 (GAL1) ELISA Kit

SEA321Hu-1x48wellstestplate 1x48-wells test plate
EUR 442.1
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Galectin 1 (GAL1) in serum, plasma, tissue homogenates and other biological fluids.

Human Galectin 1 (GAL1) ELISA Kit

SEA321Hu-1x96wellstestplate 1x96-wells test plate
EUR 580.15
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Galectin 1 (GAL1) in serum, plasma, tissue homogenates and other biological fluids.

Human Galectin 1 (GAL1) ELISA Kit

SEA321Hu-5x96wellstestplate 5x96-wells test plate
EUR 2250.68
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Galectin 1 (GAL1) in serum, plasma, tissue homogenates and other biological fluids.

Human Galectin 1 (GAL1) ELISA Kit

4-SEA321Hu
  • EUR 4152.00
  • EUR 2191.20
  • EUR 580.80
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Human Galectin 1 (GAL1) in samples from serum, plasma, tissue homogenates and other biological fluids with no significant corss-reactivity with analogues from other species.

Human Galectin 1 (GAL1) ELISA Kit

RD-GAL1-Hu-48T 48T
EUR 411.8
Description: serum, plasma, tissue homogenates, cell lysates, cell culture supernatants and other biological fluids.

Human Galectin 1 (GAL1) ELISA Kit

RD-GAL1-Hu-96T 96T
EUR 588.3
Description: serum, plasma, tissue homogenates, cell lysates, cell culture supernatants and other biological fluids.

Human Galectin 1 (GAL1) ELISA kit

YLA3564HU-48T 48T
EUR 435

Human Galectin 1 (GAL1) ELISA kit

YLA3564HU-96T 96T
EUR 562.5

Human Galectin 1 (GAL1) ELISA Kit

RDR-GAL1-Hu-48T 48T
EUR 432.39
Description: serum, plasma, tissue homogenates, cell lysates, cell culture supernatants and other biological fluids.

Human Galectin 1 (GAL1) ELISA Kit

RDR-GAL1-Hu-96T 96T
EUR 617.72
Description: serum, plasma, tissue homogenates, cell lysates, cell culture supernatants and other biological fluids.

Galectin 1 (GAL1) Polyclonal Antibody (Human)

4-PAA321Hu01
  • EUR 278.40
  • EUR 2742.00
  • EUR 688.80
  • EUR 346.80
  • EUR 249.60
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Galectin 1 (GAL1)

Galectin 1 antibody

70R-GR002 100 ug
EUR 571.2
Description: Affinity purified Rabbit polyclonal Galectin 1 antibody

Galectin 1 antibody

70R-11939 100 ug
EUR 483.6
Description: Rabbit polyclonal Galectin 1 antibody

Galectin 1 antibody

70R-13963 100 ug
EUR 386.4
Description: Affinity purified Rabbit polyclonal Galectin 1 antibody

Galectin 1 antibody

70R-49997 100 ul
EUR 292.8
Description: Purified Polyclonal Galectin 1 antibody

Galectin 1 Antibody

49673-100ul 100ul
EUR 399.6

Galectin 1 Antibody

49673-50ul 50ul
EUR 286.8

Galectin 1 Antibody

DF8089 200ul
EUR 420

Galectin 1 Antibody

DF2383 200ul
EUR 420

Galectin 1 Antibody

R31924 100 ug
EUR 356.15
Description: Galectin-1 is a protein that in humans is encoded by the LGALS1 gene. The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. Galectin-1 may act as an autocrine negative growth factor that regulates cell proliferation. Galectin-1 expression in Hodgkin Lymphoma has also been shown to mediate immunosuppression of CD8+ T-cells. It is thought to play a role in creatingimmune tolerance in pregnancy. It has been found that Galectin-1-mediated production of IL6 may assist in augmenting the innate immune response against NiV. Galectin-1 may also be a significant factor that augments the efficiency of the HIV-1 infection process.

Galectin 1 Antibody

R32841 100 ug
EUR 356.15
Description: Galectin-1 is a protein that in humans is encoded by the LGALS1 gene. The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. Galectin-1 may act as an autocrine negative growth factor that regulates cell proliferation. Galectin-1 expression in Hodgkin Lymphoma has also been shown to mediate immunosuppression of CD8+ T-cells. It is thought to play a role in creating immune tolerance in pregnancy. It has been found that Galectin-1-mediated production of IL6 may assist in augmenting the innate immune response against NiV. Galectin-1 may also be a significant factor that augments the efficiency of the HIV-1 infection process.

Galectin 1 Antibody

R32842 100 ug
EUR 356.15
Description: Galectin-1 is a protein that in humans is encoded by the LGALS1 gene. The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. Galectin-1 may act as an autocrine negative growth factor that regulates cell proliferation. Galectin-1 expression in Hodgkin Lymphoma has also been shown to mediate immunosuppression of CD8+ T-cells. It is thought to play a role in creating immune tolerance in pregnancy. It has been found that Galectin-1-mediated production of IL6 may assist in augmenting the innate immune response against NiV. Galectin-1 may also be a significant factor that augments the efficiency of the HIV-1 infection process.

Human Galectin-1 PicoKine ELISA Kit

EK0762 96 wells
EUR 510
Description: For quantitative detection of human Galectin-1 in cell culture supernates, cell lysates, serum and plasma (heparin, EDTA).

Human LGALS1/ Galectin-1 ELISA Kit

E1450Hu 1 Kit
EUR 644.4

Human LGALS1(Galectin-1) ELISA Kit

EH0626 96T
EUR 628.92
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.469 ng/ml

anti- Galectin 2 antibody

FNab03310 100µg
EUR 702
Description: Antibody raised against Galectin 2

anti- Galectin 4 antibody

FNab03311 100µg
EUR 606.3
Description: Antibody raised against Galectin 4

anti- Galectin 8 antibody

FNab03312 100µg
EUR 606.3
Description: Antibody raised against Galectin 8

anti- Galectin 9 antibody

FNab03313 100µg
EUR 606.3
Description: Antibody raised against Galectin 9

Human Galectin-7 (LGALS7)

1-CSB-RP097274h
  • EUR 456.00
  • EUR 256.80
  • EUR 1570.80
  • EUR 672.00
  • EUR 1047.60
  • EUR 314.40
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
Description: Recombinant Human Galectin-7(LGALS7) expressed in E.coli

Human Galectin-9 (LGALS9)

1-CSB-YP012895HU
  • EUR 516.00
  • EUR 280.80
  • EUR 1809.60
  • EUR 770.40
  • EUR 1210.80
  • EUR 349.20
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
Description: Recombinant Human Galectin-9(LGALS9) expressed in Yeast

Human Galectin-2 (LGALS2)

1-CSB-EP012886HU
  • EUR 456.00
  • EUR 256.80
  • EUR 1570.80
  • EUR 672.00
  • EUR 1047.60
  • EUR 314.40
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
Description: Recombinant Human Galectin-2(LGALS2) expressed in E.coli

Human Galectin-9 (LGALS9)

1-CSB-EP012895HU
  • EUR 456.00
  • EUR 256.80
  • EUR 1570.80
  • EUR 672.00
  • EUR 1047.60
  • EUR 314.40
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
Description: Recombinant Human Galectin-9(LGALS9) expressed in E.coli

Human Galectin-4 (Gal-4) Antibody

30074-05111 150 ug
EUR 313.2

Human Galectin-7 (Gal-7) Antibody

30084-05111 150 ug
EUR 313.2

Human Galectin-3 (Gal-3) Antibody

30118-05111 150 ug
EUR 313.2

Human Galectin 1 (LGALS1) ELISA Kit

20-abx151618
  • EUR 6768.00
  • EUR 3610.80
  • EUR 848.40
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Human Galectin 1 (LGALS1) ELISA Kit

abx253591-96tests 96 tests
EUR 801.6

Human Galectin 1 (LGALS1) ELISA Kit

abx351576-96tests 96 tests
EUR 801.6

Human Galectin- 1, LGALS1 ELISA KIT

ELI-06950h 96 Tests
EUR 988.8

rHu Galectin-1

AK8281-0010 10µg Ask for price

rHu Galectin-1

AK8281-0050 50µg Ask for price

rHu Galectin-1

AK8281-0100 100µg Ask for price

rHu Galectin-1

AK8281-1000 1mg Ask for price

ELISA kit for Human Galectin-1 (LGALS1)

KTE61825-48T 48T
EUR 398.4
Description: Quantitative sandwich ELISA for measuring Human Galectin-1 (LGALS1) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Human Galectin-1 (LGALS1)

KTE61825-5platesof96wells 5 plates of 96 wells
EUR 2538
Description: Quantitative sandwich ELISA for measuring Human Galectin-1 (LGALS1) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Human Galectin-1 (LGALS1)

KTE61825-96T 96T
EUR 646.8
Description: Quantitative sandwich ELISA for measuring Human Galectin-1 (LGALS1) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

Galectin-1 (LEG1) Antibody

20-abx219486
  • EUR 510.00
  • EUR 410.40
  • 100 ug
  • 50 ug

Galectin-1 (LEG1) Antibody

20-abx014039
  • EUR 376.80
  • EUR 117.60
  • EUR 477.60
  • EUR 594.00
  • 100 ug
  • 10 ug
  • 200 ug
  • 300 µg

Galectin-1 (LGAS1)

PR27143 50 ug
EUR 381.6

CLIA kit for Human GAL1 (Galectin 1 )

E-CL-H0704 1 plate of 96 wells
EUR 700.8
Description: A sandwich CLIA kit for quantitative measurement of Human GAL1 (Galectin 1 ) in samples from Serum, Plasma, Cell supernatant

Galectin 1 (GAL1) Polyclonal Antibody (Human), PE

4-PAA321Hu01-PE
  • EUR 334.80
  • EUR 2874.00
  • EUR 825.60
  • EUR 416.40
  • EUR 225.60
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Galectin 1 (GAL1). This antibody is labeled with PE.

Recombinant Human Galectin-13

7-00457 20µg Ask for price

Recombinant Human Galectin-13

7-00458 100µg Ask for price

Recombinant Human Galectin-13

7-00459 1mg Ask for price

Recombinant Human Galectin-14

7-00460 1µg Ask for price

Recombinant Human Galectin-14

7-00461 5µg Ask for price

Recombinant Human Galectin-14

7-00462 50µg Ask for price

Recombinant Human Galectin

P0197 100ug
EUR 626.83
Description: Recombinant Human protein for Galectin

ELISA kit for Human GAL1 (Galectin 1)

ELK1312 1 plate of 96 wells
EUR 446.4
Description: A sandwich ELISA kit for detection of Galectin 1 from Human in samples from blood, serum, plasma, cell culture fluid and other biological fluids.

ELISA kit for Human GAL1 (Galectin 1)

E-EL-H1051 1 plate of 96 wells
EUR 640.8
Description: A sandwich ELISA kit for quantitative measurement of Human GAL1 (Galectin 1) in samples from Serum, Plasma, Cell supernatant

Nori® Human Galectin 1 ELISA Kit

GR111389 96-well
EUR 461

Galectin 1 (GAL1) Polyclonal Antibody (Human), APC

4-PAA321Hu01-APC
  • EUR 387.60
  • EUR 3562.80
  • EUR 1003.20
  • EUR 490.80
  • EUR 252.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Galectin 1 (GAL1). This antibody is labeled with APC.

Galectin 1 (GAL1) Polyclonal Antibody (Human), Cy3

4-PAA321Hu01-Cy3
  • EUR 468.00
  • EUR 4700.40
  • EUR 1287.60
  • EUR 604.80
  • EUR 286.80
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Galectin 1 (GAL1). This antibody is labeled with Cy3.

Galectin 1 (GAL1) Polyclonal Antibody (Human), HRP

4-PAA321Hu01-HRP
  • EUR 356.40
  • EUR 3106.80
  • EUR 889.20
  • EUR 445.20
  • EUR 238.80
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Galectin 1 (GAL1). This antibody is labeled with HRP.

Galectin 1 (GAL1) Polyclonal Antibody (Human, Pig)

4-PAA321Po01
  • EUR 310.80
  • EUR 3232.80
  • EUR 800.40
  • EUR 391.20
  • EUR 261.60
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human, Pig Galectin 1 (GAL1)

Human Galectin-1 (Gal-1) AssayLite Antibody (RPE Conjugate)

30005-05151 150 ug
EUR 513.6

Human Galectin-1 (Gal-1) AssayLite Antibody (APC Conjugate)

30005-05161 150 ug
EUR 513.6

Galectin-1 (LGALS1) Antibody

abx233314-100ug 100 ug
EUR 577.2

Galectin-1 (LGALS1) Antibody

abx233315-100ug 100 ug
EUR 610.8

Galectin-1 Protein

20-abx261634
  • EUR 4101.60
  • EUR 393.60
  • EUR 276.00
  • 1 mg
  • 20 ug
  • 5 ug

Galectin-1 Protein

20-abx263505
  • EUR 276.00
  • EUR 2148.00
  • EUR 393.60
  • 10 ug
  • 1 mg
  • 50 ug

Recombinant Human Galectin-2

7-00430 5µg Ask for price

Recombinant Human Galectin-2

7-00431 25µg Ask for price

Recombinant Human Galectin-2

7-00432 1mg Ask for price

Recombinant Human Galectin-3

7-00433 10µg Ask for price

Recombinant Human Galectin-3

7-00434 50µg Ask for price

Recombinant Human Galectin-3

7-00435 1mg Ask for price

Recombinant Human Galectin-4

7-00439 5µg Ask for price

Myelin Oligodendrocyte Glycoprotein-antibody-associated Dysfunction Presenting with Corticomeningeal Encephalitis previous to the Onset of Optic Neuritis

We herein report a case of myelin oligodendrocyte glycoprotein-antibody-associated dysfunction (MOG-AD) presenting with corticomeningeal encephalitis. The affected person exhibited oral ulceration, a light impairment of consciousness, fever, nausea, nuchal rigidity, positivity for human leukocyte antigen sort B51, and neutrophil-dominant pleocytosis and interleukin-6 stage in cerebrospinal fluid (CSF). Magnetic resonance imaging (MRI) revealed a proper temporal lesion with leptomeningeal gadolinium enhancement.

The preliminary analysis was neuro-Behçet’s illness presenting with meningoencephalitis; nevertheless, a cell-based assay detected anti-MOG antibody within the serum and CSF and the affected person additionally skilled bilateral optic neuritis. After administering steroid remedy, his neurologic signs and CSF abnormalities improved together with the disappearance of gadolinium enhancement and the lesion on MRI. This case means that MOG-AD could current with corticomeningeal encephalitis previous to the onset of optic neuritis.

Excessive antibody ranges in opposition to human herpesvirus-6A work together with way of life elements in a number of sclerosis improvement

 

Background: An infection with human herpesvirus 6A (HHV-6A) has been steered to extend a number of sclerosis (MS) threat. Nonetheless, potential interactions between HHV-6A and environmental/way of life threat elements for MS haven’t beforehand been studied.

Strategies: We used two Swedish population-based case-control research comprising 5993 circumstances and 5995 controls. Utilizing logistic regression fashions, topics with completely different HHV-6A antibody ranges, environmental exposures, and way of life habits had been in contrast concerning MS threat, by calculating odds ratios (ORs) with 95% confidence intervals (CIs). Potential interactions between excessive HHV-6A antibody ranges and customary environmental exposures and way of life elements had been evaluated on the additive scale.

Outcomes: Excessive HHV-6A antibody ranges had been related to elevated threat of creating MS (OR = 1.5, 95% CI = 1.4-1.6). Concerning MS threat, important interactions had been noticed between excessive HHV-6A antibody ranges and each smoking (attributable proportion (AP) = 0.2, 95% CI = 0.1-0.3), low ultraviolet radiation (UVR) publicity (AP = 0.3, 95% CI = 0.1-0.4), and low vitamin D ranges (AP = 0.3, 95% CI = 0.0-0.6).

Conclusion: Excessive HHV-6A antibody ranges are related to elevated MS threat and act synergistically with widespread environmental/way of life threat elements for MS. Additional analysis is required to research potential mechanisms underlying the interactions introduced on this examine.

Immune subtraction for improved decision in serum protein immunofixation electrophoresis and antibody isotype willpower in a affected person with autoantibody

 

Heavy chain isotypes of low stage monoclonal immunoglobulins are generally obscured in serum immunofixation electrophoresis (SIFE) by a heavy background of polyclonal immunoglobulins. Nonetheless, correct willpower of the heavy chain isotype is important for a whole analysis, as isotype willpower of autoantibodies could have relevance in figuring out therapeutic procedures. Immune subtraction (IS) was employed in a affected person with neuropathy and GD1a autoantibody. IS allowed identification of the cognate heavy chain associated to a lambda mild chain restriction famous on preliminary SIFE in addition to isotype willpower of the autoantibody. Antisera particular to particular person heavy and lightweight chains had been used for depletion of particular immunoglobulin varieties. Depletion of kappa mild chain related immunoglobulins allowed unequivocal willpower of the isotype of lambda mild chain-associated low stage monoclonal band to be IgG Lambda. Selective depletion of kappa, lambda, gamma and mu heavy chain immunoglobulins was employed to decide IgG Kappa isotype of the auto-antibody.

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