NOTCH3-targeted antibody drug conjugates regress tumors by inducing apoptosis in receptor cells and thru transendocytosis into ligand cells
Aberrant NOTCH3 signaling and overexpression is oncogenic, related with most cancers stem cells and drug resistance, but therapeutic focusing on stays elusive. Right here, we develop NOTCH3-targeted antibody drug conjugates (NOTCH3-ADCs) by bioconjugation of an auristatin microtubule inhibitor by way of a protease cleavable linker to 2 antibodies with differential talents to inhibit signaling. The signaling inhibitory antibody quickly induces ligand-independent receptor clustering and internalization by way of each caveolin and clathrin-mediated pathways.
The non-inhibitory antibody additionally effectively endocytoses through clathrin with out inducing receptor clustering however with slower lysosomal co-localization kinetics. As well as, DLL4 ligand binding to the NOTCH3 receptor mediates transendocytosis of NOTCH3-ADCs into ligand-expressing cells. NOTCH3-ADCs internalize into receptor and ligand cells impartial of signaling and induce cell loss of life in each cell sorts representing an atypical mechanism of ADC cytotoxicity. Therapy of xenografts with NOTCH3-ADCs results in sustained tumor regressions, outperforms standard-of-care chemotherapy, and permits focusing on of tumors that overexpress NOTCH3 impartial of signaling inhibition.
Fc-binding antibody-recruiting molecules exploit endogenous antibodies for anti-tumor immune responses
Redirecting endogenous antibodies in the bloodstream to tumor cells utilizing artificial molecules is a promising method to set off anti-tumor immune responses. Nonetheless, present molecular designs solely allow the usage of a small fraction of endogenous antibodies, limiting the therapeutic potential. Right here, we report Fc-binding antibody-recruiting molecules (Fc-ARMs) as the primary instance addressing this challenge. Fc-ARMs are composed of an Fc-binding peptide and a focusing on ligand, enabling the exploitation of endogenous antibodies by way of fixed affinity to the Fc area of antibodies, whose sequence is conserved in distinction to the Fab area.
We present that Fc-ARM focusing on folate receptor-α (FR-α) redirects a clinically used antibody combination to FR-α+ most cancers cells, leading to most cancers cell lysis by pure killer cells in vitro. Fc-ARMs efficiently interacted with antibodies in vivo and collected in tumors. Moreover, Fc-ARMs recruited antibodies to suppress tumor development in a mouse mannequin. Thus, Fc-ARMs have the potential to be a novel class of most cancers immunotherapeutic brokers.

Histone H3 Methylation Antibody Panel Pack II – Active Genes |
C10002 |
EpiGentek |
|
|
Histone H3 Methylation Antibody Panel Pack II – Repression Genes |
C10003 |
EpiGentek |
|
|
Histone H3 Methylation Antibody Panel Pack III – Active Genes |
C10004 |
EpiGentek |
|
|
Histone H3K4 Methylation Antibody Panel Pack |
C10005 |
EpiGentek |
|
|
Histone H3K9 Methylation Antibody Panel Pack |
C10006 |
EpiGentek |
|
|
Histone H3K27 Methylation Antibody Panel Pack |
C10007 |
EpiGentek |
|
|
Histone H3K36 Methylation Antibody Panel Pack |
C10008 |
EpiGentek |
|
|
Histone H3K79 Methylation Antibody Panel Pack |
C10009 |
EpiGentek |
|
|
Histone H3 Acetylation Antibody Panel Pack I |
C10010 |
EpiGentek |
|
|
Histone H3 Acetylation Antibody Panel Pack II |
C10011 |
EpiGentek |
|
|
Histone H4K20 Methylation Antibody Panel Pack |
C10012 |
EpiGentek |
|
|
Histone H4 Acetylation Antibody Panel Pack |
C10013 |
EpiGentek |
|
|
Histone H3 Phosphorylation Antibody Panel Pack |
C10014 |
EpiGentek |
|
|
Histone H3R2 Methylation Antibody Panel Pack |
C10015 |
EpiGentek |
|
|
Histone H3R8 Methylation Antibody Panel Pack |
C10016 |
EpiGentek |
|
|
Histone H3R17 Methylation Antibody Panel Pack |
C10017 |
EpiGentek |
|
|
Histone H3R26 Methylation Antibody Panel Pack |
C10018 |
EpiGentek |
|
|
Histone H4R3 Methylation Antibody Panel Pack |
C10019 |
EpiGentek |
|
|
EpiMag HT (96-Well) Magnetic Separator |
Q10002 |
EpiGentek |
|
|
EpiMag 96-Well Microplate (5/pack) |
Q10003 |
EpiGentek |
|
|
DNA Methylation Antibody Panel Pack I |
C20000 |
EpiGentek |
|
|
SARS-CoV-2 Spike S1 RBD Protein, Human Fc-Fusion, Avi-Tag |
E80025 |
EpiGentek |
|
|
SARS-CoV-2 Spike S1 (13-665) Protein, Fc Fusion, Avi-tag |
E80020 |
EpiGentek |
|
|
SARS-CoV-2 Spike S1 (16-685) Protein, Avi-His-tag |
E80021 |
EpiGentek |
|
|
SARS-CoV-2 Spike S1 (16-685) Protein, Fc Fusion, Avi-tag |
E80022 |
EpiGentek |
|
|
SARS-CoV-2 Spike S1 RBD (V367F) Protein, Avi-His-tag |
E80023 |
EpiGentek |
|
|
SARS-CoV-2 Spike S1 RBD Protein, Avi-His-tag |
E80024 |
EpiGentek |
|
|
SARS-CoV-2 Spike S1 RBD Protein, Mouse Fc-fusion |
E80026 |
EpiGentek |
|
|
SARS-CoV-2 Nucleocapsid Protein, Avi-His-tag |
E80027 |
EpiGentek |
|
|
Recombinant SARS-CoV-2 Spike Glycoprotein(S) (D614G), Partial |
E80028 |
EpiGentek |
|
|
Polyclonal Goat anti-GST α-form |
GST-ANTI-1 |
Detroit R&D |
50 uL |
EUR 336 |
Anti-ALK Rabbit Monoclonal Antibody, Clone#RM361 |
M00301-1 |
BosterBio |
100uL |
EUR 462 |
Description: Anti-ALK Rabbit Monoclonal Antibody, Clone#RM361 tested in WB, IHC, reactive to Human |
Methylamp 96 DNA Modification Kit |
P-1008 |
EpiGentek |
|
|
EpiQuik Nuclear Extraction Kit |
OP-0002 |
EpiGentek |
|
- 100 Assays
- 100 Extractions
|
Nucleic Acid Isolation Enhancer (Glycogen Solution) |
R-1001 |
EpiGentek |
|
|
Methylamp PCR Enhancer |
R-1002 |
EpiGentek |
|
- 400 Reactions
- 400 Reactions
|
Streptavidin-Coated Strip Microwell Plate (Flat) |
R-1102 |
EpiGentek |
|
|
DTT Solution |
R-1104 |
EpiGentek |
|
- 1 ml, 500 mM
- 1 ml, 500 mM
|
Recombinant Transmembrane Protease Serine 2 Protein, Partial |
E80016 |
EpiGentek |
-
EUR 470.80
-
EUR 753.50
-
EUR 1824.90
|
|
Recombinant TMPRSS2 Protein, Partial |
E80017 |
EpiGentek |
-
EUR 423.50
-
EUR 660.00
-
EUR 2321.00
|
|
Recombinant Novel Coronavirus Spike Glycoprotein(S), Partial |
E80018 |
EpiGentek |
-
EUR 388.30
-
EUR 860.20
-
EUR 4888.40
|
|
Anti-human PD-1, PE-labeled |
71290-1 |
BPS Bioscience |
50 µg |
EUR 355 |
Description: R-Phycoerythrin-labeled anti-PD-1 neutralizing recombinant murine/human chimeric antibody recognizing the PD-L1/PD-L2 binding region of human PD-1. This antibody does not cross-react with mouse PD-1, but does cross-react with monkey (M. fascicularis) PD-1. It has not been tested with other species. |
Anti-EDG-1 Antibody |
A01502-1 |
BosterBio |
100ul |
EUR 476.4 |
Description: Rabbit Polyclonal Antibody for EDG-1 Antibody (S1PR1) detection.tested for WB in Human, Mouse, Rat. |
Anti-ROBO-1 Antibody |
A01530-1 |
BosterBio |
100ug |
EUR 546 |
Description: Rabbit Polyclonal ROBO-1 Antibody. Validated in IF, IHC, WB and tested in Human, Mouse, Rat. |
Anti-Bag-1 Antibody |
A02423-1 |
BosterBio |
50 ul |
EUR 476.4 |
Description: Rabbit Polyclonal Bag-1 Antibody. Validated in IP, IHC and tested in Bovine, Canine, Human, Mouse, Rat. |
Anti-TUB 1 Antibody |
A02917-1 |
BosterBio |
100ug/vial |
EUR 352.8 |
Anti-Dok-1 Antibody |
A03039-1 |
BosterBio |
100ul |
EUR 476.4 |
Description: Rabbit Polyclonal Antibody for Dok-1 Antibody (DOK1) detection.tested for WB in Human, Mouse, Rat. |
Anti-TFIIIB90-1 Antibody |
A03761-1 |
BosterBio |
100ul |
EUR 476.4 |
Description: Rabbit Polyclonal Antibody for TFIIIB90-1 Antibody (BRF1) detection.tested for WB in Human, Mouse. |
Anti-Atrophin-1 Antibody |
A03828-1 |
BosterBio |
100ul |
EUR 476.4 |
Description: Rabbit Polyclonal Antibody for Atrophin-1 Antibody (ATN1) detection. Tested with WB in Human, Mouse, Rat. |
Anti-CNG-1 Antibody |
A05494-1 |
BosterBio |
100ul |
EUR 476.4 |
Description: Rabbit Polyclonal Antibody for CNG-1 Antibody (CNGA1) detection. Tested with WB in Human, Mouse, Rat. |
Anti-Periphilin 1 Antibody |
A06996-1 |
BosterBio |
100ul |
EUR 476.4 |
Description: Rabbit Polyclonal Antibody for Periphilin 1 Antibody (PPHLN1) detection.tested for WB in Human, Mouse. |
Anti-Lyl-1 Antibody |
A07491-1 |
BosterBio |
100ul |
EUR 476.4 |
Description: Rabbit Polyclonal Lyl-1 Antibody. Validated in IHC and tested in Human, Mouse, Rat. |
Anti-GLI-1 Antibody |
A07972-1 |
BosterBio |
100ul |
EUR 476.4 |
Description: Rabbit Polyclonal Antibody for GLI-1 Antibody (ACSS1) detection. Tested with WB in Human, Mouse, Rat. |
Anti-Cerebellin 1 Antibody |
A09176-1 |
BosterBio |
100ul |
EUR 476.4 |
Description: Rabbit Polyclonal Antibody for Cerebellin 1 Antibody (CBLN1) detection. Tested with WB in Human, Mouse, Rat. |
Anti-DOC-1 Antibody |
A09467-1 |
BosterBio |
100ul |
EUR 476.4 |
Description: Rabbit Polyclonal Antibody for DOC-1 Antibody (CDK2AP1) detection. Tested with WB in Human, Mouse. |
Anti-NPDC-1 Antibody |
A12846-1 |
BosterBio |
100ul |
EUR 476.4 |
Description: Rabbit Polyclonal Antibody for NPDC-1 Antibody (NPDC1) detection. Tested with WB in Human, Mouse, Rat. |
Anti-PAI-1 Antibody |
A00637-1 |
BosterBio |
100ul |
EUR 476.4 |
Description: Rabbit Polyclonal Antibody for PAI-1 Antibody (SERPINE1) detection.tested for WB in Human, Mouse, Rat. |
Anti-Flk-1 Antibody |
A00901-1 |
BosterBio |
100ul |
EUR 476.4 |
Description: Rabbit Polyclonal Antibody for Flk-1 Antibody (KDR) detection.tested for WB in Human, Mouse. |
Anti-PARP-1 Antibody |
A00122-1 |
BosterBio |
100ul |
EUR 476.4 |
Description: Rabbit Polyclonal PARP-1 Antibody. Validated in ELISA, IP, IF, WB and tested in Human, Mouse. |
Anti-Presenilin 1 Antibody |
A00138-1 |
BosterBio |
100ul |
EUR 476.4 |
Description: Rabbit Polyclonal Antibody for Presenilin 1 Antibody (PSEN1) detection. Tested with WB, IHC in Human, Mouse, Rat. |
Anti-Apaf-1 (human) Monoclonal Antibody (2E12) |
M00889-1 |
BosterBio |
100ug |
EUR 518.4 |
Description: Rat Monoclonal Apaf-1 (human) Antibody (2E12). Validated in ELISA, IP, IF, WB and tested in Human. |
Anti-ALK-1 antibody |
STJ91563 |
St John's Laboratory |
200 µl |
EUR 236.4 |
Description: Rabbit polyclonal to ALK-1. |
Anti-ALK-1 antibody |
STJ96547 |
St John's Laboratory |
200 µl |
EUR 236.4 |
Description: Rabbit polyclonal to ALK-1. |
Anti-HO-1 Monoclonal Antibody (HO-1-2) |
M00253-1 |
BosterBio |
1mg |
EUR 476.4 |
Description: Mouse Monoclonal HO-1 Antibody (HO-1-2). Validated in Flow Cytometry, IHC, WB and tested in Human, Mouse, Rat. |
Anti-Neurexin 1/NRXN1 Antibody |
A01490-1 |
BosterBio |
100ug/vial |
EUR 400.8 |
Anti-Hexokinase 1/HK1 Antibody |
A01504-1 |
BosterBio |
100ug/vial |
EUR 400.8 |
Anti-Synaptotagmin 1/SYT1 Antibody |
A02314-1 |
BosterBio |
100ug/vial |
EUR 400.8 |
Anti-Syntenin-1 Monoclonal Antibody |
A02475-1 |
BosterBio |
100ul |
EUR 476.4 |
Description: Mouse Monoclonal Antibody for Syntenin-1 Antibody (SDCBP) detection. Tested with WB in Human, Rat, Dog, Pig. |
Anti-Dsg1/Desmoglein 1 Antibody |
A02655-1 |
BosterBio |
100ul |
EUR 476.4 |
Description: Rabbit Polyclonal Antibody for Dsg1 Antibody (DSG1) detection.tested for IHC, WB in Human, Mouse, Rat. |
Anti-CAF-1 p150 Antibody |
A02732-1 |
BosterBio |
100ul |
EUR 476.4 |
Description: Rabbit Polyclonal Antibody for CAF-1 p150 Antibody (CHAF1A) detection. Tested with WB in Human, Mouse. |
Anti-Talin 1/TLN1 Antibody |
A02859-1 |
BosterBio |
100ug/vial |
EUR 400.8 |
Anti-Islet 1/ISL1 Antibody |
A02969-1 |
BosterBio |
100ug/vial |
EUR 400.8 |
Anti-Musashi 1/Msi1 Antibody |
A05052-1 |
BosterBio |
100ug/vial |
EUR 400.8 |
Anti-Pyrophosphatase 1/PPA1 Antibody |
A07485-1 |
BosterBio |
100ug/vial |
EUR 400.8 |
Anti-TCP-1 eta Antibody |
A08169-1 |
BosterBio |
100ul |
EUR 476.4 |
Description: Rabbit Polyclonal Antibody for TCP-1 eta Antibody (CCT7) detection. Tested with WB in Human, Mouse, Rat. |
Anti-Relaxin 1/RLN1 Antibody |
A08367-1 |
BosterBio |
100ug/vial |
EUR 400.8 |
Anti-TCP-1 zeta Antibody |
A09373-1 |
BosterBio |
100ul |
EUR 476.4 |
Description: Rabbit Polyclonal Antibody for TCP-1 zeta Antibody (CCT6A) detection.tested for WB in Human, Mouse, Rat. |
Anti-Galectin 1/Lgals1 Antibody |
A00470-1 |
BosterBio |
100ug/vial |
EUR 400.8 |
Anti-LOX-1/OLR1 Antibody |
A00760-1 |
BosterBio |
100ug/vial |
EUR 352.8 |
Anti-Syndecan-1/SDC1 Antibody |
A00991-1 |
BosterBio |
100ug/vial |
EUR 352.8 |
Anti-IRAK-1/IRAK1 Antibody |
A01021-1 |
BosterBio |
100ug/vial |
EUR 400.8 |
Anti-CHST8/Galnac4St 1 Antibody |
A10989-1 |
BosterBio |
100ul |
EUR 476.4 |
Description: Rabbit Polyclonal CHST8/Galnac4St 1 Antibody. Validated in WB and tested in Human, Mouse, Rat. |
Anti-TNF Receptor 1 Antibody |
A00294-1 |
BosterBio |
200ug |
EUR 626.4 |
Description: Rabbit Polyclonal TNF Receptor 1 Antibody. Validated in IP, IHC, WB and tested in Human, Mouse, Rat. |
Anti-Galectin 1 Monoclonal Antibody |
M00470-1 |
BosterBio |
100ug |
EUR 476.4 |
Description: Rabbit Monoclonal Galectin 1 Antibody. Validated in IP, IF, WB and tested in Human, Mouse, Rat. |
Anti-DJ-1 Monoclonal Antibody |
M00757-1 |
BosterBio |
100ul |
EUR 476.4 |
Description: Mouse Monoclonal DJ-1 Antibody. Validated in IHC, WB and tested in Bovine, Human. |
Anti-Enolase 1 Monoclonal Antibody |
M01250-1 |
BosterBio |
100ul |
EUR 476.4 |
Description: Anti-Enolase 1 Monoclonal Antibody tested in WB, IF, ICC, IHC, reactive to Human, rat, mouse, cow, pig, horse |
Anti-Dynamin 1 Monoclonal Antibody |
M02536-1 |
BosterBio |
100ug |
EUR 476.4 |
Description: Rabbit Monoclonal Dynamin 1 Antibody. Validated in IF, WB and tested in Human, Mouse, Rat. |
Anti-Esrp-1 Monoclonal Antibody |
M06068-1 |
BosterBio |
100uL |
EUR 531.6 |
Description: Mouse Monoclonal Esrp-1 Antibody. Validated in WB and tested in Human. |
Anti-Presenilin 1 Monoclonal Antibody |
M00138-1 |
BosterBio |
100ug |
EUR 476.4 |
Description: Rabbit Monoclonal Presenilin 1 Antibody. Validated in WB and tested in Human, Mouse, Rat. |
Anti-Angiopoietin 1/ANGPT1 Antibody |
PA1333-1 |
BosterBio |
100ug/vial |
EUR 400.8 |
Anti-Galectin 1/LGALS1 Antibody |
PB9240-1 |
BosterBio |
100ug/vial |
EUR 400.8 |
Anti-PD-1 Agonistic Antibody |
101178-1 |
BPS Bioscience |
50 µg |
EUR 335 |
Description: Anti-PD-1 IgG antibody is a purified recombinant antibody which recognizes human PD1 antigen. This antibody has been functionally tested in two co-culture assays. |
Anti-P-glycoprotein (human) Monoclonal Antibody (JSB-1) |
M00049-1 |
BosterBio |
125ug |
EUR 703.2 |
Description: Mouse Monoclonal P-glycoprotein (human) Antibody (JSB-1). Validated in IF and tested in Human. |
Endothelin-1 (1-15), amide, human |
A1111-1 |
ApexBio |
1 mg |
EUR 866.4 |
Description: Endothelins are 21-amino acid vasoconstricting peptides produced primarily in the endothelium and have a key role in vascular homeostasis. |
Haptoglobin, (Phenotype 1-1) Human Plasma |
7536-1 |
Biovision |
each |
EUR 385.2 |
AXMIR-1 RNA oligo anti-miRNA-1-3p with Xmotif |
AXMIR-1 |
SBI |
10 reactions |
EUR 525.6 |
|
Anti-BOB-1/OBF-1 Rabbit Monoclonal Antibody, Clone#RM378 |
M04431-1 |
BosterBio |
100uL |
EUR 462 |
Description: Anti-BOB-1/OBF-1 Rabbit Monoclonal Antibody, Clone#RM378 tested in WB, IHC, reactive to Human |
Anti-HLA-G (human) Monoclonal Antibody (MEM-G/1) |
M01235-1 |
BosterBio |
100ug |
EUR 476.4 |
Description: Mouse Monoclonal HLA-G (human) Antibody (MEM-G/1). Validated in IHC, WB and tested in Human. |
Anti-Liver Carboxylesterase 1/CES1 Antibody |
A01741-1 |
BosterBio |
100ug/vial |
EUR 400.8 |
Anti-EBP50/NHERF-1/SLC9A3R1 Antibody |
A02427-1 |
BosterBio |
100ug/vial |
EUR 400.8 |
Anti-IL1R2/Il 1 Rii Antibody |
A03106-1 |
BosterBio |
1 ml |
EUR 476.4 |
Description: Rabbit Polyclonal IL1R2/Il 1 Rii Antibody. Validated in IP, WB and tested in Human. |
Anti-Hyaluronan synthase 1/HAS1 Antibody |
A04784-1 |
BosterBio |
100ug/vial |
EUR 400.8 |
Anti-CELSR3/Flamingo Homolog 1 Antibody |
A07204-1 |
BosterBio |
100ul |
EUR 476.4 |
Description: Rabbit Polyclonal CELSR3/Flamingo Homolog 1 Antibody. Validated in IF and tested in Human, Mouse, Rat. |
Anti-LPCAT2/Acyltransferase Like 1 Antibody |
A07471-1 |
BosterBio |
100ul |
EUR 476.4 |
Description: Rabbit Polyclonal LPCAT2/Acyltransferase Like 1 Antibody. Validated in WB and tested in Human, Mouse, Rat. |
Anti-VEGF Receptor 1/FLT1 Antibody |
A00534-1 |
BosterBio |
100ug/vial |
EUR 352.8 |
Anti-HIF-1 alpha/HIF1A Antibody |
A00013-1 |
BosterBio |
100ug/vial |
EUR 352.8 |
Anti-Cleaved-Notch 1 (V1754) Antibody |
A00033-1 |
BosterBio |
100ul |
EUR 476.4 |
Description: Rabbit Polyclonal Antibody for Cleaved-Notch 1 (V1754) Antibody (NOTCH1) detection.tested for WB in Human, Mouse, Rat. |
Anti-HDAC-1 (C-terminus) Antibody |
A00256-1 |
BosterBio |
100uL |
EUR 531.6 |
Description: Rabbit Polyclonal HDAC-1 (C-terminus) Antibody. Validated in IF, IHC, WB and tested in Human. |
Anti-Sumo 1 Rabbit Monoclonal Antibody |
M00631-1 |
BosterBio |
100ug/vial |
EUR 476.4 |
Description: Rabbit Monoclonal Sumo 1 Antibody. Validated in IP, IF, IHC, WB and tested in Human, Mouse, Rat. |
Anti-Cytokeratin 1 Rabbit Monoclonal Antibody |
M01639-1 |
BosterBio |
100ug/vial |
EUR 476.4 |
Description: Rabbit Monoclonal Cytokeratin 1 Antibody. Validated in WB and tested in Human, Mouse, Rat. |
Anti-Mitofusin 1 Antibody (monoclonal, 3H3) |
M02172-1 |
BosterBio |
100ug/vial |
EUR 352.8 |
Anti-Phospho-Beclin-1 (Ser295) Antibody |
P00327-1 |
BosterBio |
100ul |
EUR 477.6 |
Description: Rabbit Polyclonal Phospho-Beclin-1 (Ser295) Antibody. Validated in WB and tested in Human. |
Anti-Phospho-Raf-1 (Ser642) Antibody |
P00446-1 |
BosterBio |
100ul |
EUR 477.6 |
Description: Rabbit Polyclonal Phospho-Raf-1 (Ser642) Antibody. Validated in WB and tested in Human, Rat. |
Anti-Integrin alpha 1/ITGA1 Antibody |
PA1045-1 |
BosterBio |
100ug/vial |
EUR 400.8 |
Anti-Caspase-1(P20)/CASP1 Antibody |
PA1440-1 |
BosterBio |
100ug/vial |
EUR 352.8 |
Anti-VEGF Receptor 1/FLT1 Antibody |
PA1966-1 |
BosterBio |
100ug/vial |
EUR 352.8 |
Methylamp DNA Modification Kit |
P-1001 |
EpiGentek |
-
EUR 416.70
-
EUR 149.60
-
EUR 259.60
|
- 80 Reactions
- 40 Reactions
- 80 Reactions
|
FitAmp General Tissue Section DNA Isolation Kit |
P-1003 |
EpiGentek |
-
EUR 754.26
-
EUR 253.00
-
EUR 490.60
|
- 100 Samples
- 50 Samples
- 100 Samples
|
FitAmp Plasma/Serum DNA Isolation Kit |
P-1004 |
EpiGentek |
-
EUR 416.70
-
EUR 149.60
-
EUR 253.00
|
- 100 Samples
- 50 Samples
- 100 Samples
|
TuMinute PCR Clean-Up Kit |
P-1005 |
EpiGentek |
-
EUR 303.60
-
EUR 90.20
-
EUR 171.60
|
- 100 Samples
- 50 Samples
- 100 Samples
|
DNA Concentrator Kit |
P-1006 |
EpiGentek |
-
EUR 303.60
-
EUR 90.20
-
EUR 171.60
|
- 100 Samples
- 50 Samples
- 100 Samples
|
FitAmp Paraffin Tissue Section DNA Isolation Kit |
P-1009 |
EpiGentek |
-
EUR 702.06
-
EUR 239.80
-
EUR 454.30
|
- 100 Samples
- 50 Samples
- 100 Samples
|
Methylamp One-Step DNA Modification Kit |
P-1010 |
EpiGentek |
-
EUR 416.70
-
EUR 148.50
-
EUR 253.00
|
- 80 Samples
- 40 Samples
- 80 Samples
|
Methylamp Universal Methylated DNA Kit |
P-1011 |
EpiGentek |
-
EUR 684.66
-
EUR 292.60
-
EUR 442.20
|
- 20 Modifications
- 10 Modifications
- 20 Modifications
|
FitAmp Circulating DNA Quantification Kit |
P-1012 |
EpiGentek |
-
EUR 595.92
-
EUR 217.80
-
EUR 387.20
|
- 96 Assays
- 48 Assays
- 96 Assays
|
EpiQuik DNA Methyltransferase (DNMT) Activity/Inhibition Assay Kit |
P-3001 |
EpiGentek |
-
EUR 1050.06
-
EUR 424.60
-
EUR 712.80
|
- 96 Assays
- 48 Assays
- 96 Assays
|
EpiQuik Histone Methyltransferase Activity/Inhibition Assay Kit (H3K4) |
P-3002 |
EpiGentek |
-
EUR 1067.46
-
EUR 437.80
-
EUR 724.90
|
- 96 Assays
- 48 Assays
- 96 Assays
|
EpiQuik Histone Methyltransferase Activity/Inhibition Assay Kit (H3K9) |
P-3003 |
EpiGentek |
-
EUR 1067.46
-
EUR 437.80
-
EUR 724.90
|
- 96 Assays
- 48 Assays
- 96 Assays
|
Hemokinin 1 (human) |
B5318-1 |
ApexBio |
1 mg |
EUR 408 |
Anti-TTF-1 |
DB-089-1 |
DB Biotech |
1 ml |
EUR 900 |
Description: rabbit monospecific clonal antibodies for ihc-p application; concentrated |
Neuregulin/Heregulin-1? (NRG-1?/HRG-1?), human recombinant protein |
P1054-1 |
ApexBio |
1 mg |
EUR 4736.4 |
Description: Neuregulin (NRG) is a signaling protein for ErbB2/ErbB4 receptor heterodimers on the cardiac muscle cells and plays an important role in heart structure and function through inducing cardiomyocyte differentiation |
Anti-E74 like factor 1/ELF1 Antibody |
A03187-1 |
BosterBio |
100ug/vial |
EUR 352.8 |
Anti-GABA B Receptor 1/GABBR1 Antibody |
A07297-1 |
BosterBio |
100ug/vial |
EUR 352.8 |
Anti-Vangl1/Vang Like Protein 1 Antibody |
A07587-1 |
BosterBio |
100ul |
EUR 476.4 |
Description: Rabbit Polyclonal Antibody for Vangl1 Antibody (VANGL1) detection. Tested with WB in Human, Mouse. |
Anti-Integrin beta 1 Rabbit Monoclonal Antibody |
M00772-1 |
BosterBio |
100ug/vial |
EUR 476.4 |
Description: Rabbit Monoclonal Integrin beta 1 Antibody. Validated in IHC, WB and tested in Human, Mouse, Rat. |
Significance of hepatitis B floor antigen, IgM/IgG core antibody and hepatitis B virus DNA in blood donors
Introduction: Identification of hepatitis B virus carriers in blood donors is crucial as a way to keep away from transmission of the illness through blood transfusion.
Goal: To find out if blood donors with optimistic outcomes for serological markers HBsAg and anti-HBc have been hepatitis B virus DNA carriers.
Strategies: 12,745 samples have been collected from six Ecuadorian blood banks and analyzed for HBsAg, anti-HBc and anti-HBs infectious markers by automated ELISA. All samples that examined optimistic for one, two or all three markers have been analyzed with molecular strategies to find out the presence of viral DNA.
Outcomes: 27.5 % of the samples that have been reactive for anti-HBc alone and 100 % of these with optimistic outcomes for HbsAg and IgM/IgG anti-HBc have been recognized to include hepatitis B virus DNA (p = 0.001).
Conclusions: The collection of an infection markers, in addition to the detection strategies outline the outcomes. Performing two serological and one molecular take a look at is necessary as a way to establish hepatitis B virus carriers and forestall its transmission.
Introducción: La identificación de portadores del virus de la hepatitis B en donantes de sangre es imperativo para evitar la transmisión de la enfermedad a través de transfusiones sanguíneas.
Objetivo: Determinar si los donantes de sangre con resultados positivos en los marcadores serológicos HbsAg y anti-HBc eran portadores del ADN del virus de la hepatitis B.
Métodos: Se recolectaron 12 745 muestras de seis bancos de sangre ecuatorianos, las cuales fueron analizadas con pruebas serológicas para identificar marcadores infecciosos de HBsAg, anti-HBc, anti-HBs mediante ELISA automatizada. Todas las muestras positivas para uno, dos o los tres marcadores fueron analizadas con técnica molecular para determinar la presencia del ADN viral.
Resultados: Se identificó que 27.5 % de las muestras reactivas solo a anti-HBc y 100 % de las muestras con resultados positivos de HBsAg/anti-HBc-IgM/IgG presentaron ADN del virus de la hepatitis B (p = 0.001).
Conclusiones: La elección de los marcadores de infección y los métodos de detección definen los resultados. Es importante la realización de dos pruebas serológicas y una molecular para identificar a los portadores del virus de la hepatitis B y evitar su transmisión.
Two human antibodies to a meningococcal serogroup B vaccine antigen improve binding of complement Issue H by stabilizing the Issue H binding website
Microbial pathogens bind host complement regulatory proteins to evade the immune system. The bacterial pathogen Neisseria meningitidis, or meningococcus, binds a number of complement regulators, together with human Issue H (FH). FH binding protein (FHbp) is a element of two licensed meningococcal vaccines and in mice FHbp elicits antibodies that inhibit binding of FH to FHbp, which defeat the bacterial evasion mechanism. Nonetheless, people vaccinated with FHbp develop antibodies that improve binding of FH to the micro organism, which might restrict the effectiveness of the vaccines. Within the current examine, we present that two vaccine-elicited antibody fragments (Fabs) remoted from totally different human topics enhance binding of complement FH to meningococcal FHbp by ELISA.
The 2 Fabs have totally different results on the kinetics of FH binding to immobilized FHbp as measured by floor plasmon resonance. The 1.7- and a pair of.0-Å decision X-ray crystal constructions of the Fabs in complexes with FHbp illustrate that the 2 Fabs bind to related epitopes on the amino-terminal area of FHbp, adjoining to the FH binding website. Superposition fashions of ternary complexes of every Fab with FHbp and FH present that there’s possible minimal contact between the Fabs and FH. Collectively, the constructions reveal that the Fabs improve binding of FH to FHbp by altering the conformations and mobilities of two loops adjoining to the FH binding website of FHbp. As well as, the 1.5 Å-resolution construction of one of many remoted Fabs defines the structural rearrangements related to binding to FHbp. The FH-enhancing human Fabs, that are mirrored within the human polyclonal antibody responses, have necessary implications for tuning the effectiveness of FHbp-based vaccines.
Anti-Integrin alpha 5 Rabbit Monoclonal Antibody |
M01911 |
BosterBio |
100ug/vial |
EUR 476.4 |
Description: Rabbit Monoclonal Integrin alpha 5 Antibody. Validated in IP, IF, WB and tested in Human, Mouse, Rat. |
Alpha V Beta 5 Integrin, Peptide Aptamer, FITC labelled |
AP-301-F |
Alpha Diagnostics |
1 mg |
Ask for price |
Human Integrin Alpha 5 (ITGa5) Protein |
20-abx067272 |
Abbexa |
-
EUR 794.40
-
EUR 326.40
-
EUR 2448.00
-
EUR 944.40
-
EUR 577.20
|
- 100 ug
- 10 ug
- 1 mg
- 200 ug
- 50 ug
|
|
Integrin alpha-5 Recombinant Protein |
91-433 |
ProSci |
0.05 mg |
EUR 651.3 |
Description: Integrin alpha-5 belongs to the Integrin alpha chain family and contains 7 FG-GAP repeats. Integrin alpha-5 joins with Integrin- beta 1 to form a fibronectin and laminin receptor which recognizes the sequence R-G-D in its ligands. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions. It is expressed on fibroblasts, endothelial cells, peripheral T cells and platelets. Integrin alpha-5 undergoes post-translational cleavage in the extracellular domain to yield disulfide-linked light and heavy chains. In addition to adhesion, ITGA5 participates in cell-surface mediated signalling. |
Integrin Alpha 5 (ITGa5) Antibody |
20-abx101634 |
Abbexa |
-
EUR 493.20
-
EUR 159.60
-
EUR 1378.80
-
EUR 678.00
-
EUR 376.80
|
- 100 ug
- 10 ug
- 1 mg
- 200 ug
- 50 ug
|
|
Integrin Alpha 5 (ITGa5) Antibody |
20-abx101635 |
Abbexa |
-
EUR 560.40
-
EUR 159.60
-
EUR 1612.80
-
EUR 760.80
-
EUR 427.20
|
- 100 ug
- 10 ug
- 1 mg
- 200 ug
- 50 ug
|
|
Integrin Alpha 5 (ITGA5) Antibody |
20-abx006811 |
Abbexa |
-
EUR 493.20
-
EUR 710.40
-
EUR 218.40
-
EUR 376.80
|
- 100 ul
- 200 ul
- 20 ul
- 50 ul
|
|
Integrin Alpha 5 (ITGA5) Antibody |
20-abx000873 |
Abbexa |
|
|
|
Integrin Alpha 5 (ITGA5) Antibody |
20-abx113185 |
Abbexa |
|
|
|
Integrin Alpha 5 (ITGa5) Antibody |
20-abx129339 |
Abbexa |
-
EUR 510.00
-
EUR 159.60
-
EUR 1412.40
-
EUR 693.60
-
EUR 393.60
|
- 100 ug
- 10 ug
- 1 mg
- 200 ug
- 50 ug
|
|
Integrin Alpha 5 (ITGA5) Antibody |
abx011678-100ul |
Abbexa |
100 ul |
EUR 493.2 |
|
Integrin Alpha 5 (ITGA5) Antibody |
abx026655-400ul |
Abbexa |
400 ul |
EUR 627.6 |
|
Integrin Alpha 5 (ITGA5) Antibody |
abx026655-80l |
Abbexa |
80 µl |
EUR 343.2 |
|
Integrin alpha 5 Rabbit mAb |
A19069-100ul |
Abclonal |
100 ul |
EUR 492 |
Integrin alpha 5 Rabbit mAb |
A19069-200ul |
Abclonal |
200 ul |
EUR 685.2 |
Integrin alpha 5 Rabbit mAb |
A19069-20ul |
Abclonal |
20 ul |
EUR 265.2 |
Integrin alpha 5 Rabbit mAb |
A19069-50ul |
Abclonal |
50 ul |
EUR 344.4 |
Integrin Alpha 5 (ITGa5) Antibody |
20-abx179024 |
Abbexa |
|
|
|
Integrin Alpha 5 (ITGA5) Antibody |
20-abx338742 |
Abbexa |
-
EUR 493.20
-
EUR 2214.00
-
EUR 718.80
-
EUR 218.40
-
EUR 360.00
|
- 100 ug
- 1 mg
- 200 ug
- 20 ug
- 50 ug
|
|
Integrin alpha 5 (CD49e) Antibody |
abx216264-100ug |
Abbexa |
100 ug |
EUR 526.8 |
|
Integrin Alpha 5 (ITGA5) Antibody |
20-abx323564 |
Abbexa |
|
|
|
Integrin Alpha 5 (ITGA5) Antibody |
20-abx325454 |
Abbexa |
|
|
|
Integrin Alpha 5 (ITGA5) Antibody |
20-abx327245 |
Abbexa |
|
|
|
Integrin Alpha 5 (ITGa5) Antibody |
20-abx172956 |
Abbexa |
|
|
|
Integrin alpha 5 Conjugated Antibody |
C49269 |
SAB |
100ul |
EUR 476.4 |
Recombinant Integrin Alpha 5 (ITGa5) |
4-RPB287Bo01 |
Cloud-Clone |
-
EUR 668.35
-
EUR 302.40
-
EUR 2176.32
-
EUR 805.44
-
EUR 1490.88
-
EUR 523.20
-
EUR 5260.80
|
- 100 ug
- 10ug
- 1 mg
- 200 ug
- 500 ug
- 50ug
- 5 mg
|
|
Description: Recombinant Bovine Integrin Alpha 5 expressed in: E.coli |
Recombinant Integrin Alpha 5 (ITGa5) |
4-RPB287Hu01 |
Cloud-Clone |
-
EUR 571.58
-
EUR 276.00
-
EUR 1813.44
-
EUR 684.48
-
EUR 1248.96
-
EUR 458.40
-
EUR 4353.60
|
- 100 ug
- 10ug
- 1 mg
- 200 ug
- 500 ug
- 50ug
- 5 mg
|
|
Description: Recombinant Human Integrin Alpha 5 expressed in: E.coli |
Recombinant Integrin Alpha 5 (ITGa5) |
4-RPB287Mu01 |
Cloud-Clone |
-
EUR 571.58
-
EUR 276.00
-
EUR 1813.44
-
EUR 684.48
-
EUR 1248.96
-
EUR 458.40
-
EUR 4353.60
|
- 100 ug
- 10ug
- 1 mg
- 200 ug
- 500 ug
- 50ug
- 5 mg
|
|
Description: Recombinant Mouse Integrin Alpha 5 expressed in: E.coli |
Integrin alpha 5 Antibody (ITGA5) |
F49220-0.08ML |
NSJ Bioreagents |
0.08 ml |
EUR 165 |
Integrin alpha 5 Antibody (ITGA5) |
F41992-0.08ML |
NSJ Bioreagents |
0.08 ml |
EUR 165 |
anti-Integrin beta 5 |
YF-PA24023 |
Abfrontier |
50 ul |
EUR 400.8 |
Description: Mouse polyclonal to Integrin beta 5 |
anti-Integrin beta 5 |
YF-PA12792 |
Abfrontier |
100 ug |
EUR 483.6 |
Description: Rabbit polyclonal to Integrin beta 5 |
Rabbit Anti-Human Alpha Defensin 5 (NP-5),antiserum #1 |
HDEFA51-S |
Alpha Diagnostics |
100 ul |
EUR 548.4 |
Human Integrin Alpha 5 (ITGa5) ELISA Kit |
20-abx151987 |
Abbexa |
-
EUR 8534.40
-
EUR 4550.40
-
EUR 1054.80
|
- 10 × 96 tests
- 5 × 96 tests
- 96 tests
|
|
Human Integrin Alpha 5 (ITGa5) CLIA Kit |
20-abx492595 |
Abbexa |
-
EUR 9567.60
-
EUR 5095.20
-
EUR 1177.20
|
- 10 × 96 tests
- 5 × 96 tests
- 96 tests
|
|
Human Integrin Alpha 5 (ITGA5) ELISA Kit |
abx571172-96tests |
Abbexa |
96 tests |
EUR 886.8 |
|
Human Integrin alpha-5(ITGA5) Elisa kit |
CSB-E17350h-24T |
Cusabio |
1 plate of 24 wells |
EUR 198 |
|
Description: Quantitativesandwich ELISA kit for measuring Human Integrin alpha-5 (ITGA5) in samples from serum, plasma, cell culture supernates, urine, cerebrospinalfluid (CSF). A new trial version of the kit, which allows you to test the kit in your application at a reasonable price. |
Human Integrin alpha-5(ITGA5) Elisa kit |
1-CSB-E17350h |
Cusabio |
-
EUR 1080.00
-
EUR 6571.20
-
EUR 3480.00
|
- 1 plate of 96 wells
- 10 plates of 96 wells each
- 5 plates of 96 wells each
|
|
Description: Quantitativesandwich ELISA kit for measuring Human Integrin alpha-5(ITGA5) in samples from serum, plasma, cell culture supernates, urine, cerebrospinalfluid(CSF). Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits. |
Human Integrin Alpha 5 (ITGa5) ELISA Kit |
DLR-ITGa5-Hu-48T |
DL Develop |
48T |
EUR 597.6 |
|
Description: A sandwich quantitative ELISA assay kit for detection of Human Integrin Alpha 5 (ITGa5) in samples from tissue homogenates, cell lysates or other biological fluids. |
Human Integrin Alpha 5 (ITGa5) ELISA Kit |
DLR-ITGa5-Hu-96T |
DL Develop |
96T |
EUR 776.4 |
|
Description: A sandwich quantitative ELISA assay kit for detection of Human Integrin Alpha 5 (ITGa5) in samples from tissue homogenates, cell lysates or other biological fluids. |
Integrin Alpha 5 (ITGa5) Polyclonal Antibody (Human) |
4-PAB287Hu01 |
Cloud-Clone |
-
EUR 286.80
-
EUR 2869.20
-
EUR 717.60
-
EUR 358.80
-
EUR 253.20
|
- 100ul
- 10ml
- 1ml
- 200ul
- 20ul
|
|
Description: A Rabbit polyclonal antibody against Human Integrin Alpha 5 (ITGa5) |
Human ITGA5(Integrin alpha-5) ELISA Kit |
EH2445 |
FN Test |
96T |
EUR 681.12 |
|
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.094 ng/ml |
Human ITGA5/ Integrin alpha-5 ELISA Kit |
E1342Hu |
Sunlong |
1 Kit |
EUR 726 |
ELISA kit for Human Integrin alpha-5 |
EK4913 |
SAB |
96 tests |
EUR 804 |
Description: Enzyme-linked immunosorbent assay kit for quantification of Human Integrin alpha-5 in samples from serum, plasma, tissue homogenates and other biological fluids. |
Human Integrin Alpha 5 (ITGa5) ELISA Kit |
SEB287Hu-10x96wellstestplate |
Cloud-Clone |
10x96-wells test plate |
EUR 5402.92 |
|
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Integrin Alpha 5 (ITGa5) in Tissue homogenates, cell lysates and other biological fluids. |
Human Integrin Alpha 5 (ITGa5) ELISA Kit |
SEB287Hu-1x48wellstestplate |
Cloud-Clone |
1x48-wells test plate |
EUR 550.13 |
|
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Integrin Alpha 5 (ITGa5) in Tissue homogenates, cell lysates and other biological fluids. |
Human Integrin Alpha 5 (ITGa5) ELISA Kit |
SEB287Hu-1x96wellstestplate |
Cloud-Clone |
1x96-wells test plate |
EUR 734.46 |
|
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Integrin Alpha 5 (ITGa5) in Tissue homogenates, cell lysates and other biological fluids. |
Human Integrin Alpha 5 (ITGa5) ELISA Kit |
4-SEB287Hu |
Cloud-Clone |
-
EUR 5463.60
-
EUR 2886.00
-
EUR 735.60
|
- 10 plates of 96 wells
- 5 plates of 96 wells
- 1 plate of 96 wells
|
|
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Human Integrin Alpha 5 (ITGa5) in samples from Tissue homogenates, cell lysates and other biological fluids with no significant corss-reactivity with analogues from other species. This is a cost efficient bulk pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits to avoid unsealing the plates and reagents that won't be immediately used. |
Human Integrin Alpha 5 (ITGa5) ELISA Kit |
SEB287Hu-5x96wellstestplate |
Cloud-Clone |
5x96-wells test plate |
EUR 2945.08 |
|
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Integrin Alpha 5 (ITGa5) in Tissue homogenates, cell lysates and other biological fluids. |
Human Integrin Alpha 5 (ITGa5) ELISA Kit |
RDR-ITGa5-Hu-48Tests |
Reddot Biotech |
48 Tests |
EUR 626.4 |
Human Integrin Alpha 5 (ITGa5) ELISA Kit |
RDR-ITGa5-Hu-96Tests |
Reddot Biotech |
96 Tests |
EUR 868.8 |
Human Integrin Alpha 5 (ITGa5) ELISA Kit |
RD-ITGa5-Hu-48Tests |
Reddot Biotech |
48 Tests |
EUR 600 |
Human Integrin Alpha 5 (ITGa5) ELISA Kit |
RD-ITGa5-Hu-96Tests |
Reddot Biotech |
96 Tests |
EUR 830.4 |
Mouse Anti Human Integrin Alpha V Beta 5 Monoclonal Antibody |
CABT-49626MH |
Creative Diagnostics |
0.1 mg |
EUR 1650 |
Anti-alpha 5 beta 1 Integrin (Volociximab), Human IgG4 Antibody |
A1092-200 |
Biovision |
each |
EUR 874.8 |
Anti-Integrin alpha antibody |
STJ93727 |
St John's Laboratory |
200 µl |
EUR 236.4 |
Description: Rabbit polyclonal to Integrin alpha3. |
Anti-Integrin alpha antibody |
STJ93728 |
St John's Laboratory |
200 µl |
EUR 236.4 |
Description: Rabbit polyclonal to Integrin alpha4. |
Anti-Integrin alpha antibody |
STJ93729 |
St John's Laboratory |
200 µl |
EUR 236.4 |
Description: Rabbit polyclonal to Integrin alphaE. |
Anti-Integrin alpha antibody |
STJ93730 |
St John's Laboratory |
200 µl |
EUR 236.4 |
Description: Rabbit polyclonal to Integrin alphaV. |
Anti-Integrin alpha antibody |
STJ98181 |
St John's Laboratory |
100 µl |
EUR 280.8 |
Description: Mouse monoclonal to Integrin alpha5. |
Anti-Integrin alpha antibody |
STJ98510 |
St John's Laboratory |
100 µl |
EUR 280.8 |
Description: Mouse monoclonal to Integrin alpha5. |
Anti-Integrin alpha antibody |
STJ98511 |
St John's Laboratory |
100 µl |
EUR 280.8 |
Description: Mouse monoclonal to Integrin alpha6. |
Anti-Integrin alpha antibody |
STJ98709 |
St John's Laboratory |
200 µl |
EUR 236.4 |
Description: Rabbit polyclonal to Integrin alpha1. |
Anti-Integrin alpha antibody |
STJ98737 |
St John's Laboratory |
200 µl |
EUR 236.4 |
Description: Rabbit polyclonal to Integrin alphaX. |
Anti-Integrin alpha antibody |
STJ98984 |
St John's Laboratory |
200 µl |
EUR 236.4 |
Description: Rabbit polyclonal to Integrin alphaE. |
Anti-Integrin alpha antibody |
STJ96613 |
St John's Laboratory |
200 µl |
EUR 236.4 |
Description: Rabbit polyclonal to Integrin alpha4. |
Anti-Integrin alpha antibody |
STJ96825 |
St John's Laboratory |
200 µl |
EUR 236.4 |
Description: Rabbit polyclonal to Integrin alphaD. |
Anti-Integrin alpha antibody |
STJ97273 |
St John's Laboratory |
200 µl |
EUR 236.4 |
Description: Rabbit polyclonal to Integrin alphaL. |
Anti-Integrin alpha antibody |
STJ97283 |
St John's Laboratory |
200 µl |
EUR 236.4 |
Description: Rabbit polyclonal to Integrin alpha2. |
Anti-Integrin alpha antibody |
STJ97284 |
St John's Laboratory |
200 µl |
EUR 236.4 |
Description: Integrin alpha5 is a protein encoded by the ITGA5 gene which is approximately 114,5 kDa. Integrin alpha5 is localised to the cell membrane and is involved in the MAPK-Erk pathway, apoptotic pathways, integrin pathway, focal adhesion and blood-brain barrier and immune cell transmigration. Integrins are heterodimeric integral membrane proteins composed of an alpha subunit and a beta subunit that function in cell surface adhesion and signalling. Integrin alpha5 is expressed in the liver, lung, nervous system, bone marrow and blood. Mutations in the ITGA5 gene may result in colon carcinoma and congenital epulis STJ97284 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of Integrin alpha5 protein. |
Anti-Integrin alpha antibody |
STJ97285 |
St John's Laboratory |
200 µl |
EUR 236.4 |
Description: Rabbit polyclonal to Integrin alpha6. |
Anti-Integrin alpha antibody |
STJ97657 |
St John's Laboratory |
200 µl |
EUR 236.4 |
Description: Rabbit polyclonal to Integrin alpha3. |
anti-Integrin alpha 6 |
YF-PA24004 |
Abfrontier |
50 ul |
EUR 400.8 |
Description: Mouse polyclonal to Integrin alpha 6 |
anti-Integrin alpha 1 |
YF-PA24011 |
Abfrontier |
50 ul |
EUR 400.8 |
Description: Mouse polyclonal to Integrin alpha 1 |
anti-Integrin alpha 4 |
YF-PA24013 |
Abfrontier |
50 ul |
EUR 400.8 |
Description: Mouse polyclonal to Integrin alpha 4 |
anti-Integrin alpha 9 |
YF-PA24015 |
Abfrontier |
50 ul |
EUR 400.8 |
Description: Mouse polyclonal to Integrin alpha 9 |
anti-Integrin alpha E |
YF-PA24017 |
Abfrontier |
50 ul |
EUR 400.8 |
Description: Mouse polyclonal to Integrin alpha E |
anti-Integrin alpha 6 |
YF-PA12761 |
Abfrontier |
50 ul |
EUR 435.6 |
Description: Mouse polyclonal to Integrin alpha 6 |
anti-Integrin alpha 6 |
YF-PA12762 |
Abfrontier |
100 ug |
EUR 483.6 |
Description: Rabbit polyclonal to Integrin alpha 6 |
anti-Integrin alpha 1 |
YF-PA12784 |
Abfrontier |
50 ug |
EUR 435.6 |
Description: Mouse polyclonal to Integrin alpha 1 |
anti-Integrin alpha 4 |
YF-PA12785 |
Abfrontier |
100 ug |
EUR 483.6 |
Description: Rabbit polyclonal to Integrin alpha 4 |
anti-Integrin alpha V |
YF-PA12786 |
Abfrontier |
50 ul |
EUR 435.6 |
Description: Mouse polyclonal to Integrin alpha V |
anti-Integrin alpha V |
YF-PA12787 |
Abfrontier |
50 ug |
EUR 435.6 |
Description: Mouse polyclonal to Integrin alpha V |
anti-Integrin alpha V |
YF-PA12788 |
Abfrontier |
100 ug |
EUR 483.6 |
Description: Rabbit polyclonal to Integrin alpha V |
Mouse Integrin Alpha 5 (ITGa5) Protein |
20-abx168338 |
Abbexa |
-
EUR 794.40
-
EUR 326.40
-
EUR 2448.00
-
EUR 944.40
-
EUR 577.20
|
- 100 ug
- 10 ug
- 1 mg
- 200 ug
- 50 ug
|
|
Cow Integrin Alpha 5 (ITGa5) Protein |
20-abx067274 |
Abbexa |
-
EUR 927.60
-
EUR 360.00
-
EUR 2932.80
-
EUR 1111.20
-
EUR 661.20
|
- 100 ug
- 10 ug
- 1 mg
- 200 ug
- 50 ug
|
|
Integrin alpha 5 recombinant monoclonal antibody |
A5201 |
Bimake |
100ul X 3 |
EUR 714 |
|
Description: A recombinant monoclonal antibody from rabbit against human Integrin alpha 5 for WB,ELISA |
Integrin Alpha 5 (ITGA5) Antibody (HRP) |
20-abx336126 |
Abbexa |
-
EUR 493.20
-
EUR 2214.00
-
EUR 718.80
-
EUR 218.40
-
EUR 360.00
|
- 100 ug
- 1 mg
- 200 ug
- 20 ug
- 50 ug
|
|
Integrin Alpha 5 (ITGA5) Antibody (FITC) |
20-abx336127 |
Abbexa |
-
EUR 493.20
-
EUR 2214.00
-
EUR 718.80
-
EUR 218.40
-
EUR 360.00
|
- 100 ug
- 1 mg
- 200 ug
- 20 ug
- 50 ug
|
|
Integrin Alpha 5 (ITGA5) Antibody (Biotin) |
20-abx336128 |
Abbexa |
-
EUR 493.20
-
EUR 2214.00
-
EUR 718.80
-
EUR 218.40
-
EUR 360.00
|
- 100 ug
- 1 mg
- 200 ug
- 20 ug
- 50 ug
|
|
Integrin Alpha 5 (ITGA5) Antibody (FITC) |
abx413989-01mg |
Abbexa |
0.1 mg |
EUR 610.8 |
|
Integrin alpha 5 (CD49e) Blocking Peptide |
AF5200-BP |
Affbiotech |
1mg |
EUR 234 |
Rabbit Anti-Human Alpha Defensin 5 (NP-5),, IgG #1, aff pure |
HDEFA51-A |
Alpha Diagnostics |
100 ug |
EUR 578.4 |
anti- Integrin beta-5 antibody |
FNab04352 |
FN Test |
100µg |
EUR 606.3 |
|
Description: Antibody raised against Integrin beta-5 |
Anti-Integrin beta 5 (1D8) |
YF-MA13874 |
Abfrontier |
100 ug |
EUR 435.6 |
Description: Mouse monoclonal to Integrin beta 5 |
Anti-Integrin ß-5 Antibody |
A1832-100 |
Biovision |
each |
EUR 418.8 |
Anti-Integrin ß-5 Antibody |
A1832-30T |
Biovision |
each |
EUR 175.2 |
Integrin Alpha 5 (ITGa5) Polyclonal Antibody (Human), APC |
4-PAB287Hu01-APC |
Cloud-Clone |
-
EUR 399.60
-
EUR 3735.60
-
EUR 1046.40
-
EUR 507.60
-
EUR 258.00
|
- 100ul
- 10ml
- 1ml
- 200ul
- 20ul
|
|
Description: A Rabbit polyclonal antibody against Human Integrin Alpha 5 (ITGa5). This antibody is labeled with APC. |
Integrin Alpha 5 (ITGa5) Polyclonal Antibody (Human), Biotinylated |
4-PAB287Hu01-Biotin |
Cloud-Clone |
-
EUR 363.60
-
EUR 2809.20
-
EUR 836.40
-
EUR 442.80
-
EUR 259.20
|
- 100ul
- 10ml
- 1ml
- 200ul
- 20ul
|
|
Description: A Rabbit polyclonal antibody against Human Integrin Alpha 5 (ITGa5). This antibody is labeled with Biotin. |
Integrin Alpha 5 (ITGa5) Polyclonal Antibody (Human), Cy3 |
4-PAB287Hu01-Cy3 |
Cloud-Clone |
-
EUR 483.60
-
EUR 4930.80
-
EUR 1345.20
-
EUR 627.60
-
EUR 294.00
|
- 100ul
- 10ml
- 1ml
- 200ul
- 20ul
|
|
Description: A Rabbit polyclonal antibody against Human Integrin Alpha 5 (ITGa5). This antibody is labeled with Cy3. |
Integrin Alpha 5 (ITGa5) Polyclonal Antibody (Human), FITC |
4-PAB287Hu01-FITC |
Cloud-Clone |
-
EUR 344.40
-
EUR 3012.00
-
EUR 860.40
-
EUR 430.80
-
EUR 230.40
|
- 100ul
- 10ml
- 1ml
- 200ul
- 20ul
|
|
Description: A Rabbit polyclonal antibody against Human Integrin Alpha 5 (ITGa5). This antibody is labeled with FITC. |
Integrin Alpha 5 (ITGa5) Polyclonal Antibody (Human), HRP |
4-PAB287Hu01-HRP |
Cloud-Clone |
-
EUR 366.00
-
EUR 3256.80
-
EUR 926.40
-
EUR 459.60
-
EUR 243.60
|
- 100ul
- 10ml
- 1ml
- 200ul
- 20ul
|
|
Description: A Rabbit polyclonal antibody against Human Integrin Alpha 5 (ITGa5). This antibody is labeled with HRP. |
Integrin Alpha 5 (ITGa5) Polyclonal Antibody (Human), PE |
4-PAB287Hu01-PE |
Cloud-Clone |
-
EUR 344.40
-
EUR 3012.00
-
EUR 860.40
-
EUR 430.80
-
EUR 230.40
|
- 100ul
- 10ml
- 1ml
- 200ul
- 20ul
|
|
Description: A Rabbit polyclonal antibody against Human Integrin Alpha 5 (ITGa5). This antibody is labeled with PE. |
ELISA kit for Human ITGa5 (Integrin Alpha 5) |
ELK3746 |
ELK Biotech |
1 plate of 96 wells |
EUR 518.4 |
|
Description: A sandwich ELISA kit for detection of Integrin Alpha 5 from Human in samples from blood, serum, plasma, cell culture fluid and other biological fluids. |
Recombinant Antibody to Integrin Alpha 5 (ITGa5) (Human) |
4-RAB287Hu21 |
Cloud-Clone |
-
EUR 406.80
-
EUR 4754.40
-
EUR 1146.00
-
EUR 530.40
-
EUR 303.60
|
- 100ul
- 10ml
- 1ml
- 200ul
- 20ul
|
|
Description: A Recombinant antibody against Human Integrin Alpha 5 (ITGa5) |
Rabbit Polyclonal antibody Anti-CRBN |
Anti-CRBN |
ImmunoStep |
50 µg |
EUR 418.8 |
Cow Integrin Alpha 5 (ITGA5) ELISA Kit |
abx521007-96tests |
Abbexa |
96 tests |
EUR 1093.2 |
|
Mouse Integrin Alpha 5 (ITGA5) ELISA Kit |
abx521009-96tests |
Abbexa |
96 tests |
EUR 886.8 |
|
Integrin Alpha 5 (ITGa5) Polyclonal Antibody (Bovine) |
4-PAB287Bo01 |
Cloud-Clone |
-
EUR 320.40
-
EUR 3391.20
-
EUR 836.40
-
EUR 405.60
-
EUR 266.40
|
- 100ul
- 10ml
- 1ml
- 200ul
- 20ul
|
|
Description: A Rabbit polyclonal antibody against Bovine Integrin Alpha 5 (ITGa5) |
Integrin Alpha 5 (ITGa5) Polyclonal Antibody (Mouse) |
4-PAB287Mu01 |
Cloud-Clone |
-
EUR 291.60
-
EUR 2948.40
-
EUR 735.60
-
EUR 366.00
-
EUR 254.40
|
- 100ul
- 10ml
- 1ml
- 200ul
- 20ul
|
|
Description: A Rabbit polyclonal antibody against Mouse Integrin Alpha 5 (ITGa5) |
ELISA kit for Mouse Integrin alpha-5 |
EK4914 |
SAB |
96 tests |
EUR 804 |
Description: Enzyme-linked immunosorbent assay kit for quantification of Mouse Integrin alpha-5 in samples from serum, plasma, tissue homogenates and other biological fluids. |
Mouse Itga5/ Integrin alpha-5 ELISA Kit |
E0812Mo |
Sunlong |
1 Kit |
EUR 758.4 |
Bovine Integrin alpha- 5, ITGA5 ELISA KIT |
ELI-07693b |
Lifescience Market |
96 Tests |
EUR 1113.6 |
anti- Integrin alpha-1 antibody |
FNab04343 |
FN Test |
100µg |
EUR 702 |
|
Description: Antibody raised against Integrin alpha-1 |
anti- Integrin alpha-3 antibody |
FNab04344 |
FN Test |
100µg |
EUR 702 |
|
Description: Antibody raised against Integrin alpha-3 |
anti- Integrin alpha-3 antibody |
FNab04345 |
FN Test |
100µg |
EUR 702 |
|
Description: Antibody raised against Integrin alpha-3 |
anti- Integrin alpha-4 antibody |
FNab04346 |
FN Test |
100µg |
EUR 606.3 |
|
Description: Antibody raised against Integrin alpha-4 |
anti- Integrin alpha-9 antibody |
FNab04348 |
FN Test |
100µg |
EUR 606.3 |
|
Description: Antibody raised against Integrin alpha-9 |
Anti-Integrin alpha 6 (4C1) |
YF-MA13842 |
Abfrontier |
100 ug |
EUR 435.6 |
Description: Mouse monoclonal to Integrin alpha 6 |
Anti-Integrin alpha 1 (4G11) |
YF-MA13866 |
Abfrontier |
100 ug |
EUR 435.6 |
Description: Mouse monoclonal to Integrin alpha 1 |
Anti-Integrin alpha 4 (2G10) |
YF-MA13867 |
Abfrontier |
100 ug |
EUR 435.6 |
Description: Mouse monoclonal to Integrin alpha 4 |
Anti-Integrin alpha 9 (3E4) |
YF-MA13869 |
Abfrontier |
100 ug |
EUR 435.6 |
Description: Mouse monoclonal to Integrin alpha 9 |
Anti-Integrin alpha E (6B8) |
YF-MA13870 |
Abfrontier |
100 ug |
EUR 435.6 |
Description: Mouse monoclonal to Integrin alpha E |
Anti-Integrin alpha 4 (2C11) |
YF-MA10493 |
Abfrontier |
100 ug |
EUR 435.6 |
Description: Mouse monoclonal to Integrin alpha 4 |
Integrin Alpha 5 (ITGa5) Polyclonal Antibody (Human), APC-Cy7 |
4-PAB287Hu01-APC-Cy7 |
Cloud-Clone |
-
EUR 656.40
-
EUR 7327.20
-
EUR 1948.80
-
EUR 872.40
-
EUR 372.00
|
- 100ul
- 10ml
- 1ml
- 200ul
- 20ul
|
|
Description: A Rabbit polyclonal antibody against Human Integrin Alpha 5 (ITGa5). This antibody is labeled with APC-Cy7. |
Recombinant Antibody to Integrin Alpha 5 (ITGa5) (Human), APC |
4-RAB287Hu21-APC |
Cloud-Clone |
-
EUR 580.80
-
EUR 6306.00
-
EUR 1688.40
-
EUR 765.60
-
EUR 333.60
|
- 100ul
- 10ml
- 1ml
- 200ul
- 20ul
|
|
Description: A Recombinant antibody against Human Integrin Alpha 5 (ITGa5). This antibody is labeled with APC. |
Recombinant Antibody to Integrin Alpha 5 (ITGa5) (Human), Biotinylated |
4-RAB287Hu21-Biotin |
Cloud-Clone |
-
EUR 495.60
-
EUR 4694.40
-
EUR 1308.00
-
EUR 631.20
-
EUR 314.40
|
- 100ul
- 10ml
- 1ml
- 200ul
- 20ul
|
|
Description: A Recombinant antibody against Human Integrin Alpha 5 (ITGa5). This antibody is labeled with Biotin. |