NOTCH3-targeted antibody drug conjugates regress tumors by inducing apoptosis in receptor cells and thru transendocytosis into ligand cells

 

Aberrant NOTCH3 signaling and overexpression is oncogenic, related with most cancers stem cells and drug resistance, but therapeutic focusing on stays elusive. Right here, we develop NOTCH3-targeted antibody drug conjugates (NOTCH3-ADCs) by bioconjugation of an auristatin microtubule inhibitor by way of a protease cleavable linker to 2 antibodies with differential talents to inhibit signaling. The signaling inhibitory antibody quickly induces ligand-independent receptor clustering and internalization by way of each caveolin and clathrin-mediated pathways.

The non-inhibitory antibody additionally effectively endocytoses through clathrin with out inducing receptor clustering however with slower lysosomal co-localization kinetics. As well as, DLL4 ligand binding to the NOTCH3 receptor mediates transendocytosis of NOTCH3-ADCs into ligand-expressing cells. NOTCH3-ADCs internalize into receptor and ligand cells impartial of signaling and induce cell loss of life in each cell sorts representing an atypical mechanism of ADC cytotoxicity. Therapy of xenografts with NOTCH3-ADCs results in sustained tumor regressions, outperforms standard-of-care chemotherapy, and permits focusing on of tumors that overexpress NOTCH3 impartial of signaling inhibition.

Fc-binding antibody-recruiting molecules exploit endogenous antibodies for anti-tumor immune responses

Redirecting endogenous antibodies in the bloodstream to tumor cells utilizing artificial molecules is a promising method to set off anti-tumor immune responses. Nonetheless, present molecular designs solely allow the usage of a small fraction of endogenous antibodies, limiting the therapeutic potential. Right here, we report Fc-binding antibody-recruiting molecules (Fc-ARMs) as the primary instance addressing this challenge. Fc-ARMs are composed of an Fc-binding peptide and a focusing on ligand, enabling the exploitation of endogenous antibodies by way of fixed affinity to the Fc area of antibodies, whose sequence is conserved in distinction to the Fab area.

We present that Fc-ARM focusing on folate receptor-α (FR-α) redirects a clinically used antibody combination to FR-α⁺ most cancers cells, leading to most cancers cell lysis by pure killer cells in vitro. Fc-ARMs efficiently interacted with antibodies in vivo and collected in tumors. Moreover, Fc-ARMs recruited antibodies to suppress tumor development in a mouse mannequin. Thus, Fc-ARMs have the potential to be a novel class of most cancers immunotherapeutic brokers.

Histone H3 Methylation Antibody Panel Pack II – Active Genes
C10002	EpiGentek	EUR 754.26 EUR 470.80	3 x 25 µg 3 x 25 ul

Histone H3 Methylation Antibody Panel Pack II – Repression Genes
C10003	EpiGentek	EUR 928.26 EUR 588.50	4 x 25 µg 4 x 25 ul

Histone H3 Methylation Antibody Panel Pack III – Active Genes
C10004	EpiGentek	EUR 928.26 EUR 588.50	4 x 25 µg 4 x 25 ul

Histone H3K4 Methylation Antibody Panel Pack
C10005	EpiGentek	EUR 754.26 EUR 470.80	3 x 25 µg 3 x 25 ul

Histone H3K9 Methylation Antibody Panel Pack
C10006	EpiGentek	EUR 754.26 EUR 470.80	3 x 25 µg 3 x 25 ul

Histone H3K27 Methylation Antibody Panel Pack
C10007	EpiGentek	EUR 754.26 EUR 470.80	3 x 25 µg 3 x 25 ul

Histone H3K36 Methylation Antibody Panel Pack
C10008	EpiGentek	EUR 754.26 EUR 470.80	3 x 25 µg 3 x 25 ul

Histone H3K79 Methylation Antibody Panel Pack
C10009	EpiGentek	EUR 754.26 EUR 470.80	3 x 25 µg 3 x 25 ul

Histone H3 Acetylation Antibody Panel Pack I
C10010	EpiGentek	EUR 928.26 EUR 588.50	4 x 25 µg 4 x 25 ul

Histone H3 Acetylation Antibody Panel Pack II
C10011	EpiGentek	EUR 928.26 EUR 588.50	4 x 25 µg 4 x 25 ul

Histone H4K20 Methylation Antibody Panel Pack
C10012	EpiGentek	EUR 754.26 EUR 470.80	3 x 25 µg 3 x 25 ul

Histone H4 Acetylation Antibody Panel Pack
C10013	EpiGentek	EUR 754.26 EUR 470.80	4 x 25 µg 4 x 25 ul

Histone H3 Phosphorylation Antibody Panel Pack
C10014	EpiGentek	EUR 754.26 EUR 470.80	3 x 25 µg 3 x 25 ul

Histone H3R2 Methylation Antibody Panel Pack
C10015	EpiGentek	EUR 754.26 EUR 470.80	3 x 25 µg 3 x 25 ul

Histone H3R8 Methylation Antibody Panel Pack
C10016	EpiGentek	EUR 754.26 EUR 470.80	3 x 25 µg 3 x 25 ul

Histone H3R17 Methylation Antibody Panel Pack
C10017	EpiGentek	EUR 754.26 EUR 470.80	3 x 25 µg 3 x 25 ul

Histone H3R26 Methylation Antibody Panel Pack
C10018	EpiGentek	EUR 754.26 EUR 470.80	3 x 25 µg 3 x 25 ul

Histone H4R3 Methylation Antibody Panel Pack
C10019	EpiGentek	EUR 754.26 EUR 470.80	3 x 25 µg 3 x 25 ul

DNMT3A Protein
E11000	EpiGentek	EUR 971.76 EUR 618.20	10 µg 10 ul

TET1 Protein (Active)
E12002	EpiGentek	EUR 387.12 EUR 225.50	10 µg 10 ul

DNMT3B Protein
E14000	EpiGentek	EUR 971.76 EUR 618.20	10 µg 10 ul

DNMT1 Protein
E15000	EpiGentek	EUR 971.76 EUR 618.20	10 µg 10 ul

HDAC1 Protein
E24002	EpiGentek	EUR 968.28 EUR 616.00	50 µg 50 ul

HDAC10 Protein
E24003	EpiGentek	EUR 968.28 EUR 616.00	50 µg 50 ul

HDAC11 Protein
E24004	EpiGentek	EUR 968.28 EUR 616.00	50 µg 50 ul

HDAC2 Protein
E24005	EpiGentek	EUR 968.28 EUR 616.00	50 µg 50 ul

HDAC3 Protein
E24006	EpiGentek	EUR 968.28 EUR 616.00	50 µg 50 ul

HDAC4 Protein
E24007	EpiGentek	EUR 968.28 EUR 616.00	10 µg 10 ul

HDAC5 Protein
E24008	EpiGentek	EUR 968.28 EUR 616.00	10 µg 10 ul

HDAC6 Protein
E24009	EpiGentek	EUR 968.28 EUR 616.00	50 µg 50 ul

HDAC7 Protein
E24010	EpiGentek	EUR 968.28 EUR 616.00	10 µg 10 ul

HDAC8 Protein
E24011	EpiGentek	EUR 968.28 EUR 616.00	50 µg 50 ul

HDAC9 Protein
E24012	EpiGentek	EUR 968.28 EUR 616.00	10 µg 10 ul

H3F3A Protein
E35003	EpiGentek	EUR 174.84 EUR 78.10	50 µg 50 ul

H4 Protein
E35005	EpiGentek	EUR 174.84 EUR 78.10	50 µg 50 ul

SOD1 Protein
E70000	EpiGentek	EUR 599.40 EUR 365.20	25 µg 25 ul

EpiMag HT (96-Well) Magnetic Separator
Q10002	EpiGentek	EUR 416.70 EUR 258.50	1/Pack 1/Pack

EpiMag 96-Well Microplate (5/pack)
Q10003	EpiGentek	EUR 136.56 EUR 52.80	5/pack 5/pack

DNA Methylation Antibody Panel Pack I
C20000	EpiGentek	EUR 458.46 EUR 270.60	each 2 x 25 ul

SARS-CoV-2 Spike S1 RBD Protein, Human Fc-Fusion, Avi-Tag
E80025	EpiGentek	EUR 635.80 EUR 3934.70	100 ul 1 ml

ACE2, His-Tag Protein
E80019	EpiGentek	EUR 612.70 EUR 1437.70	20 ul 100 ul

SARS-CoV-2 Spike S1 (13-665) Protein, Fc Fusion, Avi-tag
E80020	EpiGentek	EUR 635.80 EUR 4276.80	100 ul 1 ml

SARS-CoV-2 Spike S1 (16-685) Protein, Avi-His-tag
E80021	EpiGentek	EUR 635.80 EUR 4276.80	100 ul 1 ml

SARS-CoV-2 Spike S1 (16-685) Protein, Fc Fusion, Avi-tag
E80022	EpiGentek	EUR 635.80 EUR 4276.80	100 ul 1 ml

SARS-CoV-2 Spike S1 RBD (V367F) Protein, Avi-His-tag
E80023	EpiGentek	EUR 635.80 EUR 3934.70	100 ul 1 ml

SARS-CoV-2 Spike S1 RBD Protein, Avi-His-tag
E80024	EpiGentek	EUR 635.80 EUR 4995.10	100 ul 1 ml

SARS-CoV-2 Spike S1 RBD Protein, Mouse Fc-fusion
E80026	EpiGentek	EUR 588.50 EUR 823.90	20 ul 50 ul

SARS-CoV-2 Nucleocapsid Protein, Avi-His-tag
E80027	EpiGentek	EUR 635.80 EUR 4087.60	1 ml 100 ul

Recombinant SARS-CoV-2 Spike Glycoprotein(S) (D614G), Partial
E80028	EpiGentek	EUR 388.30 EUR 860.20	20 ul 100 ul

Polyclonal Goat anti-GST α-form
GST-ANTI-1	Detroit R&D	50 uL	EUR 336

Anti-ALK Rabbit Monoclonal Antibody, Clone#RM361
M00301-1	BosterBio	100uL	EUR 462
Description: Anti-ALK Rabbit Monoclonal Antibody, Clone#RM361 tested in WB, IHC, reactive to Human

Methylamp 96 DNA Modification Kit
P-1008	EpiGentek	EUR 416.70 EUR 253.00	96 Samples 96 Samples

EpiQuik Nuclear Extraction Kit
OP-0002	EpiGentek	EUR 350.58 EUR 211.20	100 Assays 100 Extractions

Nucleic Acid Isolation Enhancer (Glycogen Solution)
R-1001	EpiGentek	EUR 164.40 EUR 75.90	500 µl 500 ul

Methylamp PCR Enhancer
R-1002	EpiGentek	EUR 185.28 EUR 90.20	400 Reactions 400 Reactions

Streptavidin: HRP Conjugate
R-1098	EpiGentek	EUR 218.34 EUR 107.80	0.5 ml 0.5 ml

Streptavidin
R-1100	EpiGentek	EUR 237.48 EUR 121.00	1 mg 1 ml

Protease Inhibitor Cocktail
R-1101	EpiGentek	EUR 176.58 EUR 79.20	1 ml 1 ml

Streptavidin-Coated Strip Microwell Plate (Flat)
R-1102	EpiGentek	EUR 361.02 EUR 204.60	5/pk 5/pk

DNA High Binding Solution
R-1103	EpiGentek	EUR 267.06 EUR 140.80	30 ml 30 ml

DTT Solution
R-1104	EpiGentek	EUR 131.34 EUR 48.40	1 ml, 500 mM 1 ml, 500 mM

Recombinant Transmembrane Protease Serine 2 Protein, Partial
E80016	EpiGentek	EUR 470.80 EUR 753.50 EUR 1824.90	20 ul 100 ul 500 ul

Recombinant TMPRSS2 Protein, Partial
E80017	EpiGentek	EUR 423.50 EUR 660.00 EUR 2321.00	20 ul 100 ul 1 ml

Recombinant Novel Coronavirus Spike Glycoprotein(S), Partial
E80018	EpiGentek	EUR 388.30 EUR 860.20 EUR 4888.40	20 ul 100 ul 1 ml

Anti-human PD-1, PE-labeled
71290-1	BPS Bioscience	50 µg	EUR 355
Description: R-Phycoerythrin-labeled anti-PD-1 neutralizing recombinant murine/human chimeric antibody recognizing the PD-L1/PD-L2 binding region of human PD-1. This antibody does not cross-react with mouse PD-1, but does cross-react with monkey (M. fascicularis) PD-1. It has not been tested with other species.

Anti-EDG-1 Antibody
A01502-1	BosterBio	100ul	EUR 476.4
Description: Rabbit Polyclonal Antibody for EDG-1 Antibody (S1PR1) detection.tested for WB in Human, Mouse, Rat.

Anti-ROBO-1 Antibody
A01530-1	BosterBio	100ug	EUR 546
Description: Rabbit Polyclonal ROBO-1 Antibody. Validated in IF, IHC, WB and tested in Human, Mouse, Rat.

Anti-Bag-1 Antibody
A02423-1	BosterBio	50 ul	EUR 476.4
Description: Rabbit Polyclonal Bag-1 Antibody. Validated in IP, IHC and tested in Bovine, Canine, Human, Mouse, Rat.

Anti-TUB 1 Antibody
A02917-1	BosterBio	100ug/vial	EUR 352.8

Anti-Dok-1 Antibody
A03039-1	BosterBio	100ul	EUR 476.4
Description: Rabbit Polyclonal Antibody for Dok-1 Antibody (DOK1) detection.tested for WB in Human, Mouse, Rat.

Anti-TFIIIB90-1 Antibody
A03761-1	BosterBio	100ul	EUR 476.4
Description: Rabbit Polyclonal Antibody for TFIIIB90-1 Antibody (BRF1) detection.tested for WB in Human, Mouse.

Anti-Atrophin-1 Antibody
A03828-1	BosterBio	100ul	EUR 476.4
Description: Rabbit Polyclonal Antibody for Atrophin-1 Antibody (ATN1) detection. Tested with WB in Human, Mouse, Rat.

Anti-CNG-1 Antibody
A05494-1	BosterBio	100ul	EUR 476.4
Description: Rabbit Polyclonal Antibody for CNG-1 Antibody (CNGA1) detection. Tested with WB in Human, Mouse, Rat.

Anti-Periphilin 1 Antibody
A06996-1	BosterBio	100ul	EUR 476.4
Description: Rabbit Polyclonal Antibody for Periphilin 1 Antibody (PPHLN1) detection.tested for WB in Human, Mouse.

Anti-Lyl-1 Antibody
A07491-1	BosterBio	100ul	EUR 476.4
Description: Rabbit Polyclonal Lyl-1 Antibody. Validated in IHC and tested in Human, Mouse, Rat.

Anti-GLI-1 Antibody
A07972-1	BosterBio	100ul	EUR 476.4
Description: Rabbit Polyclonal Antibody for GLI-1 Antibody (ACSS1) detection. Tested with WB in Human, Mouse, Rat.

Anti-Cerebellin 1 Antibody
A09176-1	BosterBio	100ul	EUR 476.4
Description: Rabbit Polyclonal Antibody for Cerebellin 1 Antibody (CBLN1) detection. Tested with WB in Human, Mouse, Rat.

Anti-DOC-1 Antibody
A09467-1	BosterBio	100ul	EUR 476.4
Description: Rabbit Polyclonal Antibody for DOC-1 Antibody (CDK2AP1) detection. Tested with WB in Human, Mouse.

Anti-NPDC-1 Antibody
A12846-1	BosterBio	100ul	EUR 476.4
Description: Rabbit Polyclonal Antibody for NPDC-1 Antibody (NPDC1) detection. Tested with WB in Human, Mouse, Rat.

Anti-PAI-1 Antibody
A00637-1	BosterBio	100ul	EUR 476.4
Description: Rabbit Polyclonal Antibody for PAI-1 Antibody (SERPINE1) detection.tested for WB in Human, Mouse, Rat.

Anti-Flk-1 Antibody
A00901-1	BosterBio	100ul	EUR 476.4
Description: Rabbit Polyclonal Antibody for Flk-1 Antibody (KDR) detection.tested for WB in Human, Mouse.

Anti-PARP-1 Antibody
A00122-1	BosterBio	100ul	EUR 476.4
Description: Rabbit Polyclonal PARP-1 Antibody. Validated in ELISA, IP, IF, WB and tested in Human, Mouse.

Anti-Presenilin 1 Antibody
A00138-1	BosterBio	100ul	EUR 476.4
Description: Rabbit Polyclonal Antibody for Presenilin 1 Antibody (PSEN1) detection. Tested with WB, IHC in Human, Mouse, Rat.

Anti-Apaf-1 (human) Monoclonal Antibody (2E12)
M00889-1	BosterBio	100ug	EUR 518.4
Description: Rat Monoclonal Apaf-1 (human) Antibody (2E12). Validated in ELISA, IP, IF, WB and tested in Human.

Anti-ALK-1 antibody
STJ91563	St John's Laboratory	200 µl	EUR 236.4
Description: Rabbit polyclonal to ALK-1.

Anti-ALK-1 antibody
STJ96547	St John's Laboratory	200 µl	EUR 236.4
Description: Rabbit polyclonal to ALK-1.

Anti-HO-1 Monoclonal Antibody (HO-1-2)
M00253-1	BosterBio	1mg	EUR 476.4
Description: Mouse Monoclonal HO-1 Antibody (HO-1-2). Validated in Flow Cytometry, IHC, WB and tested in Human, Mouse, Rat.

Anti-Neurexin 1/NRXN1 Antibody
A01490-1	BosterBio	100ug/vial	EUR 400.8

Anti-Hexokinase 1/HK1 Antibody
A01504-1	BosterBio	100ug/vial	EUR 400.8

Anti-Synaptotagmin 1/SYT1 Antibody
A02314-1	BosterBio	100ug/vial	EUR 400.8

Anti-Syntenin-1 Monoclonal Antibody
A02475-1	BosterBio	100ul	EUR 476.4
Description: Mouse Monoclonal Antibody for Syntenin-1 Antibody (SDCBP) detection. Tested with WB in Human, Rat, Dog, Pig.

Anti-Dsg1/Desmoglein 1 Antibody
A02655-1	BosterBio	100ul	EUR 476.4
Description: Rabbit Polyclonal Antibody for Dsg1 Antibody (DSG1) detection.tested for IHC, WB in Human, Mouse, Rat.

Anti-CAF-1 p150 Antibody
A02732-1	BosterBio	100ul	EUR 476.4
Description: Rabbit Polyclonal Antibody for CAF-1 p150 Antibody (CHAF1A) detection. Tested with WB in Human, Mouse.

Anti-Talin 1/TLN1 Antibody
A02859-1	BosterBio	100ug/vial	EUR 400.8

Anti-Islet 1/ISL1 Antibody
A02969-1	BosterBio	100ug/vial	EUR 400.8

Anti-Musashi 1/Msi1 Antibody
A05052-1	BosterBio	100ug/vial	EUR 400.8

Anti-Pyrophosphatase 1/PPA1 Antibody
A07485-1	BosterBio	100ug/vial	EUR 400.8

Anti-TCP-1 eta Antibody
A08169-1	BosterBio	100ul	EUR 476.4
Description: Rabbit Polyclonal Antibody for TCP-1 eta Antibody (CCT7) detection. Tested with WB in Human, Mouse, Rat.

Anti-Relaxin 1/RLN1 Antibody
A08367-1	BosterBio	100ug/vial	EUR 400.8

Anti-TCP-1 zeta Antibody
A09373-1	BosterBio	100ul	EUR 476.4
Description: Rabbit Polyclonal Antibody for TCP-1 zeta Antibody (CCT6A) detection.tested for WB in Human, Mouse, Rat.

Anti-Galectin 1/Lgals1 Antibody
A00470-1	BosterBio	100ug/vial	EUR 400.8

Anti-LOX-1/OLR1 Antibody
A00760-1	BosterBio	100ug/vial	EUR 352.8

Anti-Syndecan-1/SDC1 Antibody
A00991-1	BosterBio	100ug/vial	EUR 352.8

Anti-IRAK-1/IRAK1 Antibody
A01021-1	BosterBio	100ug/vial	EUR 400.8

Anti-CHST8/Galnac4St 1 Antibody
A10989-1	BosterBio	100ul	EUR 476.4
Description: Rabbit Polyclonal CHST8/Galnac4St 1 Antibody. Validated in WB and tested in Human, Mouse, Rat.

Anti-TNF Receptor 1 Antibody
A00294-1	BosterBio	200ug	EUR 626.4
Description: Rabbit Polyclonal TNF Receptor 1 Antibody. Validated in IP, IHC, WB and tested in Human, Mouse, Rat.

Anti-Galectin 1 Monoclonal Antibody
M00470-1	BosterBio	100ug	EUR 476.4
Description: Rabbit Monoclonal Galectin 1 Antibody. Validated in IP, IF, WB and tested in Human, Mouse, Rat.

Anti-DJ-1 Monoclonal Antibody
M00757-1	BosterBio	100ul	EUR 476.4
Description: Mouse Monoclonal DJ-1 Antibody. Validated in IHC, WB and tested in Bovine, Human.

Anti-Enolase 1 Monoclonal Antibody
M01250-1	BosterBio	100ul	EUR 476.4
Description: Anti-Enolase 1 Monoclonal Antibody tested in WB, IF, ICC, IHC, reactive to Human, rat, mouse, cow, pig, horse

Anti-Dynamin 1 Monoclonal Antibody
M02536-1	BosterBio	100ug	EUR 476.4
Description: Rabbit Monoclonal Dynamin 1 Antibody. Validated in IF, WB and tested in Human, Mouse, Rat.

Anti-Esrp-1 Monoclonal Antibody
M06068-1	BosterBio	100uL	EUR 531.6
Description: Mouse Monoclonal Esrp-1 Antibody. Validated in WB and tested in Human.

Anti-Presenilin 1 Monoclonal Antibody
M00138-1	BosterBio	100ug	EUR 476.4
Description: Rabbit Monoclonal Presenilin 1 Antibody. Validated in WB and tested in Human, Mouse, Rat.

Anti-Angiopoietin 1/ANGPT1 Antibody
PA1333-1	BosterBio	100ug/vial	EUR 400.8

Anti-Galectin 1/LGALS1 Antibody
PB9240-1	BosterBio	100ug/vial	EUR 400.8

Anti-PD-1 Agonistic Antibody
101178-1	BPS Bioscience	50 µg	EUR 335
Description: Anti-PD-1 IgG antibody is a purified recombinant antibody which recognizes human PD1 antigen. This antibody has been functionally tested in two co-culture assays.

Anti-P-glycoprotein (human) Monoclonal Antibody (JSB-1)
M00049-1	BosterBio	125ug	EUR 703.2
Description: Mouse Monoclonal P-glycoprotein (human) Antibody (JSB-1). Validated in IF and tested in Human.

Endothelin-1 (1-15), amide, human
A1111-1	ApexBio	1 mg	EUR 866.4
Description: Endothelins are 21-amino acid vasoconstricting peptides produced primarily in the endothelium and have a key role in vascular homeostasis.

Haptoglobin, (Phenotype 1-1) Human Plasma
7536-1	Biovision	each	EUR 385.2

AXMIR-1 RNA oligo anti-miRNA-1-3p with Xmotif
AXMIR-1	SBI	10 reactions	EUR 525.6

Anti-BOB-1/OBF-1 Rabbit Monoclonal Antibody, Clone#RM378
M04431-1	BosterBio	100uL	EUR 462
Description: Anti-BOB-1/OBF-1 Rabbit Monoclonal Antibody, Clone#RM378 tested in WB, IHC, reactive to Human

Anti-HLA-G (human) Monoclonal Antibody (MEM-G/1)
M01235-1	BosterBio	100ug	EUR 476.4
Description: Mouse Monoclonal HLA-G (human) Antibody (MEM-G/1). Validated in IHC, WB and tested in Human.

Anti-Liver Carboxylesterase 1/CES1 Antibody
A01741-1	BosterBio	100ug/vial	EUR 400.8

Anti-EBP50/NHERF-1/SLC9A3R1 Antibody
A02427-1	BosterBio	100ug/vial	EUR 400.8

Anti-IL1R2/Il 1 Rii Antibody
A03106-1	BosterBio	1 ml	EUR 476.4
Description: Rabbit Polyclonal IL1R2/Il 1 Rii Antibody. Validated in IP, WB and tested in Human.

Anti-Hyaluronan synthase 1/HAS1 Antibody
A04784-1	BosterBio	100ug/vial	EUR 400.8

Anti-CELSR3/Flamingo Homolog 1 Antibody
A07204-1	BosterBio	100ul	EUR 476.4
Description: Rabbit Polyclonal CELSR3/Flamingo Homolog 1 Antibody. Validated in IF and tested in Human, Mouse, Rat.

Anti-LPCAT2/Acyltransferase Like 1 Antibody
A07471-1	BosterBio	100ul	EUR 476.4
Description: Rabbit Polyclonal LPCAT2/Acyltransferase Like 1 Antibody. Validated in WB and tested in Human, Mouse, Rat.

Anti-VEGF Receptor 1/FLT1 Antibody
A00534-1	BosterBio	100ug/vial	EUR 352.8

Anti-HIF-1 alpha/HIF1A Antibody
A00013-1	BosterBio	100ug/vial	EUR 352.8

Anti-Cleaved-Notch 1 (V1754) Antibody
A00033-1	BosterBio	100ul	EUR 476.4
Description: Rabbit Polyclonal Antibody for Cleaved-Notch 1 (V1754) Antibody (NOTCH1) detection.tested for WB in Human, Mouse, Rat.

Anti-HDAC-1 (C-terminus) Antibody
A00256-1	BosterBio	100uL	EUR 531.6
Description: Rabbit Polyclonal HDAC-1 (C-terminus) Antibody. Validated in IF, IHC, WB and tested in Human.

Anti-Sumo 1 Rabbit Monoclonal Antibody
M00631-1	BosterBio	100ug/vial	EUR 476.4
Description: Rabbit Monoclonal Sumo 1 Antibody. Validated in IP, IF, IHC, WB and tested in Human, Mouse, Rat.

Anti-Cytokeratin 1 Rabbit Monoclonal Antibody
M01639-1	BosterBio	100ug/vial	EUR 476.4
Description: Rabbit Monoclonal Cytokeratin 1 Antibody. Validated in WB and tested in Human, Mouse, Rat.

Anti-Mitofusin 1 Antibody (monoclonal, 3H3)
M02172-1	BosterBio	100ug/vial	EUR 352.8

Anti-Phospho-Beclin-1 (Ser295) Antibody
P00327-1	BosterBio	100ul	EUR 477.6
Description: Rabbit Polyclonal Phospho-Beclin-1 (Ser295) Antibody. Validated in WB and tested in Human.

Anti-Phospho-Raf-1 (Ser642) Antibody
P00446-1	BosterBio	100ul	EUR 477.6
Description: Rabbit Polyclonal Phospho-Raf-1 (Ser642) Antibody. Validated in WB and tested in Human, Rat.

Anti-Integrin alpha 1/ITGA1 Antibody
PA1045-1	BosterBio	100ug/vial	EUR 400.8

Anti-Caspase-1(P20)/CASP1 Antibody
PA1440-1	BosterBio	100ug/vial	EUR 352.8

Anti-VEGF Receptor 1/FLT1 Antibody
PA1966-1	BosterBio	100ug/vial	EUR 352.8

Methylamp DNA Modification Kit
P-1001	EpiGentek	EUR 416.70 EUR 149.60 EUR 259.60	80 Reactions 40 Reactions 80 Reactions

FitAmp General Tissue Section DNA Isolation Kit
P-1003	EpiGentek	EUR 754.26 EUR 253.00 EUR 490.60	100 Samples 50 Samples 100 Samples

FitAmp Plasma/Serum DNA Isolation Kit
P-1004	EpiGentek	EUR 416.70 EUR 149.60 EUR 253.00	100 Samples 50 Samples 100 Samples

TuMinute PCR Clean-Up Kit
P-1005	EpiGentek	EUR 303.60 EUR 90.20 EUR 171.60	100 Samples 50 Samples 100 Samples

DNA Concentrator Kit
P-1006	EpiGentek	EUR 303.60 EUR 90.20 EUR 171.60	100 Samples 50 Samples 100 Samples

FitAmp Paraffin Tissue Section DNA Isolation Kit
P-1009	EpiGentek	EUR 702.06 EUR 239.80 EUR 454.30	100 Samples 50 Samples 100 Samples

Methylamp One-Step DNA Modification Kit
P-1010	EpiGentek	EUR 416.70 EUR 148.50 EUR 253.00	80 Samples 40 Samples 80 Samples

Methylamp Universal Methylated DNA Kit
P-1011	EpiGentek	EUR 684.66 EUR 292.60 EUR 442.20	20 Modifications 10 Modifications 20 Modifications

FitAmp Circulating DNA Quantification Kit
P-1012	EpiGentek	EUR 595.92 EUR 217.80 EUR 387.20	96 Assays 48 Assays 96 Assays

EpiQuik DNA Methyltransferase (DNMT) Activity/Inhibition Assay Kit
P-3001	EpiGentek	EUR 1050.06 EUR 424.60 EUR 712.80	96 Assays 48 Assays 96 Assays

EpiQuik Histone Methyltransferase Activity/Inhibition Assay Kit (H3K4)
P-3002	EpiGentek	EUR 1067.46 EUR 437.80 EUR 724.90	96 Assays 48 Assays 96 Assays

EpiQuik Histone Methyltransferase Activity/Inhibition Assay Kit (H3K9)
P-3003	EpiGentek	EUR 1067.46 EUR 437.80 EUR 724.90	96 Assays 48 Assays 96 Assays

Hemokinin 1 (human)
B5318-1	ApexBio	1 mg	EUR 408

Anti-TTF-1
DB-089-1	DB Biotech	1 ml	EUR 900
Description: rabbit monospecific clonal antibodies for ihc-p application; concentrated

Neuregulin/Heregulin-1? (NRG-1?/HRG-1?), human recombinant protein
P1054-1	ApexBio	1 mg	EUR 4736.4
Description: Neuregulin (NRG) is a signaling protein for ErbB2/ErbB4 receptor heterodimers on the cardiac muscle cells and plays an important role in heart structure and function through inducing cardiomyocyte differentiation

Anti-E74 like factor 1/ELF1 Antibody
A03187-1	BosterBio	100ug/vial	EUR 352.8

Anti-GABA B Receptor 1/GABBR1 Antibody
A07297-1	BosterBio	100ug/vial	EUR 352.8

Anti-Vangl1/Vang Like Protein 1 Antibody
A07587-1	BosterBio	100ul	EUR 476.4
Description: Rabbit Polyclonal Antibody for Vangl1 Antibody (VANGL1) detection. Tested with WB in Human, Mouse.

Anti-Integrin beta 1 Rabbit Monoclonal Antibody
M00772-1	BosterBio	100ug/vial	EUR 476.4
Description: Rabbit Monoclonal Integrin beta 1 Antibody. Validated in IHC, WB and tested in Human, Mouse, Rat.

Significance of hepatitis B floor antigen, IgM/IgG core antibody and hepatitis B virus DNA in blood donors

Introduction: Identification of hepatitis B virus carriers in blood donors is crucial as a way to keep away from transmission of the illness through blood transfusion.

Goal: To find out if blood donors with optimistic outcomes for serological markers HBsAg and anti-HBc have been hepatitis B virus DNA carriers.

Strategies: 12,745 samples have been collected from six Ecuadorian blood banks and analyzed for HBsAg, anti-HBc and anti-HBs infectious markers by automated ELISA. All samples that examined optimistic for one, two or all three markers have been analyzed with molecular strategies to find out the presence of viral DNA.

Outcomes: 27.5 % of the samples that have been reactive for anti-HBc alone and 100 % of these with optimistic outcomes for HbsAg and IgM/IgG anti-HBc have been recognized to include hepatitis B virus DNA (p = 0.001).

Conclusions: The collection of an infection markers, in addition to the detection strategies outline the outcomes. Performing two serological and one molecular take a look at is necessary as a way to establish hepatitis B virus carriers and forestall its transmission.

Introducción: La identificación de portadores del virus de la hepatitis B en donantes de sangre es imperativo para evitar la transmisión de la enfermedad a través de transfusiones sanguíneas.

Objetivo: Determinar si los donantes de sangre con resultados positivos en los marcadores serológicos HbsAg y anti-HBc eran portadores del ADN del virus de la hepatitis B.

Métodos: Se recolectaron 12 745 muestras de seis bancos de sangre ecuatorianos, las cuales fueron analizadas con pruebas serológicas para identificar marcadores infecciosos de HBsAg, anti-HBc, anti-HBs mediante ELISA automatizada. Todas las muestras positivas para uno, dos o los tres marcadores fueron analizadas con técnica molecular para determinar la presencia del ADN viral.

Resultados: Se identificó que 27.5 % de las muestras reactivas solo a anti-HBc y 100 % de las muestras con resultados positivos de HBsAg/anti-HBc-IgM/IgG presentaron ADN del virus de la hepatitis B (p = 0.001).

Conclusiones: La elección de los marcadores de infección y los métodos de detección definen los resultados. Es importante la realización de dos pruebas serológicas y una molecular para identificar a los portadores del virus de la hepatitis B y evitar su transmisión.

Two human antibodies to a meningococcal serogroup B vaccine antigen improve binding of complement Issue H by stabilizing the Issue H binding website

Microbial pathogens bind host complement regulatory proteins to evade the immune system. The bacterial pathogen Neisseria meningitidis, or meningococcus, binds a number of complement regulators, together with human Issue H (FH). FH binding protein (FHbp) is a element of two licensed meningococcal vaccines and in mice FHbp elicits antibodies that inhibit binding of FH to FHbp, which defeat the bacterial evasion mechanism. Nonetheless, people vaccinated with FHbp develop antibodies that improve binding of FH to the micro organism, which might restrict the effectiveness of the vaccines. Within the current examine, we present that two vaccine-elicited antibody fragments (Fabs) remoted from totally different human topics enhance binding of complement FH to meningococcal FHbp by ELISA.

The 2 Fabs have totally different results on the kinetics of FH binding to immobilized FHbp as measured by floor plasmon resonance. The 1.7- and a pair of.0-Å decision X-ray crystal constructions of the Fabs in complexes with FHbp illustrate that the 2 Fabs bind to related epitopes on the amino-terminal area of FHbp, adjoining to the FH binding website. Superposition fashions of ternary complexes of every Fab with FHbp and FH present that there’s possible minimal contact between the Fabs and FH. Collectively, the constructions reveal that the Fabs improve binding of FH to FHbp by altering the conformations and mobilities of two loops adjoining to the FH binding website of FHbp. As well as, the 1.5 Å-resolution construction of one of many remoted Fabs defines the structural rearrangements related to binding to FHbp. The FH-enhancing human Fabs, that are mirrored within the human polyclonal antibody responses, have necessary implications for tuning the effectiveness of FHbp-based vaccines.

 

Integrin alpha 5 Antibody
R31667	NSJ Bioreagents	100 ug	EUR 419

Integrin alpha 5 Antibody
F49220-0.4ML	NSJ Bioreagents	0.4 ml	EUR 379

Integrin alpha 5 Antibody
F41992-0.4ML	NSJ Bioreagents	0.4 ml	EUR 379

Anti-Integrin alpha 5 Rabbit Monoclonal Antibody
M01911	BosterBio	100ug/vial	EUR 476.4
Description: Rabbit Monoclonal Integrin alpha 5 Antibody. Validated in IP, IF, WB and tested in Human, Mouse, Rat.

Alpha V Beta 5 Integrin, Peptide Aptamer, FITC labelled
AP-301-F	Alpha Diagnostics	1 mg	Ask for price

Human Integrin Alpha 5 (ITGa5) Protein
20-abx067272	Abbexa	EUR 794.40 EUR 326.40 EUR 2448.00 EUR 944.40 EUR 577.20	100 ug 10 ug 1 mg 200 ug 50 ug

Integrin alpha-5 Recombinant Protein
91-433	ProSci	0.05 mg	EUR 651.3
Description: Integrin alpha-5 belongs to the Integrin alpha chain family and contains 7 FG-GAP repeats. Integrin alpha-5 joins with Integrin- beta 1 to form a fibronectin and laminin receptor which recognizes the sequence R-G-D in its ligands. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions. It is expressed on fibroblasts, endothelial cells, peripheral T cells and platelets. Integrin alpha-5 undergoes post-translational cleavage in the extracellular domain to yield disulfide-linked light and heavy chains. In addition to adhesion, ITGA5 participates in cell-surface mediated signalling.

Integrin Alpha 5 (ITGa5) Antibody
20-abx101634	Abbexa	EUR 493.20 EUR 159.60 EUR 1378.80 EUR 678.00 EUR 376.80	100 ug 10 ug 1 mg 200 ug 50 ug

Integrin Alpha 5 (ITGa5) Antibody
20-abx101635	Abbexa	EUR 560.40 EUR 159.60 EUR 1612.80 EUR 760.80 EUR 427.20	100 ug 10 ug 1 mg 200 ug 50 ug

Integrin Alpha 5 (ITGA5) Antibody
20-abx006811	Abbexa	EUR 493.20 EUR 710.40 EUR 218.40 EUR 376.80	100 ul 200 ul 20 ul 50 ul

Integrin Alpha 5 (ITGA5) Antibody
20-abx000873	Abbexa	EUR 493.20 EUR 710.40	100 ul 200 ul

Integrin Alpha 5 (ITGA5) Antibody
20-abx113185	Abbexa	EUR 878.40 EUR 477.60	150 ul 50 ul

Integrin Alpha 5 (ITGa5) Antibody
20-abx129339	Abbexa	EUR 510.00 EUR 159.60 EUR 1412.40 EUR 693.60 EUR 393.60	100 ug 10 ug 1 mg 200 ug 50 ug

Integrin Alpha 5 (ITGA5) Antibody
abx011678-100ul	Abbexa	100 ul	EUR 493.2

Integrin Alpha 5 (ITGA5) Antibody
abx026655-400ul	Abbexa	400 ul	EUR 627.6

Integrin Alpha 5 (ITGA5) Antibody
abx026655-80l	Abbexa	80 µl	EUR 343.2

Integrin alpha 5 Rabbit mAb
A19069-100ul	Abclonal	100 ul	EUR 492

Integrin alpha 5 Rabbit mAb
A19069-200ul	Abclonal	200 ul	EUR 685.2

Integrin alpha 5 Rabbit mAb
A19069-20ul	Abclonal	20 ul	EUR 265.2

Integrin alpha 5 Rabbit mAb
A19069-50ul	Abclonal	50 ul	EUR 344.4

Integrin Alpha 5 (ITGa5) Antibody
20-abx179024	Abbexa	EUR 2013.60 EUR 927.60	1 mg 200 ug

Integrin Alpha 5 (ITGA5) Antibody
20-abx338742	Abbexa	EUR 493.20 EUR 2214.00 EUR 718.80 EUR 218.40 EUR 360.00	100 ug 1 mg 200 ug 20 ug 50 ug

Integrin alpha 5 (CD49e) Antibody
abx216264-100ug	Abbexa	100 ug	EUR 526.8

Integrin Alpha 5 (ITGA5) Antibody
20-abx323564	Abbexa	EUR 376.80 EUR 292.80	100 ug 50 ug

Integrin Alpha 5 (ITGA5) Antibody
20-abx325454	Abbexa	EUR 376.80 EUR 292.80	100 ug 50 ug

Integrin Alpha 5 (ITGA5) Antibody
20-abx327245	Abbexa	EUR 376.80 EUR 292.80	100 ug 50 ug

Integrin Alpha 5 (ITGa5) Antibody
20-abx172956	Abbexa	EUR 978.00 EUR 510.00	1 mg 200 ug

Integrin alpha 5 Conjugated Antibody
C49269	SAB	100ul	EUR 476.4

Recombinant Integrin Alpha 5 (ITGa5)
4-RPB287Bo01	Cloud-Clone	EUR 668.35 EUR 302.40 EUR 2176.32 EUR 805.44 EUR 1490.88 EUR 523.20 EUR 5260.80	100 ug 10ug 1 mg 200 ug 500 ug 50ug 5 mg
Description: Recombinant Bovine Integrin Alpha 5 expressed in: E.coli

Recombinant Integrin Alpha 5 (ITGa5)
4-RPB287Hu01	Cloud-Clone	EUR 571.58 EUR 276.00 EUR 1813.44 EUR 684.48 EUR 1248.96 EUR 458.40 EUR 4353.60	100 ug 10ug 1 mg 200 ug 500 ug 50ug 5 mg
Description: Recombinant Human Integrin Alpha 5 expressed in: E.coli

Recombinant Integrin Alpha 5 (ITGa5)
4-RPB287Mu01	Cloud-Clone	EUR 571.58 EUR 276.00 EUR 1813.44 EUR 684.48 EUR 1248.96 EUR 458.40 EUR 4353.60	100 ug 10ug 1 mg 200 ug 500 ug 50ug 5 mg
Description: Recombinant Mouse Integrin Alpha 5 expressed in: E.coli

Integrin alpha 5 Antibody / ITGA5
RQ4096	NSJ Bioreagents	100 ug	EUR 419

Integrin alpha 5 Antibody (ITGA5)
F49220-0.08ML	NSJ Bioreagents	0.08 ml	EUR 165

Integrin alpha 5 Antibody (ITGA5)
F41992-0.08ML	NSJ Bioreagents	0.08 ml	EUR 165

Integrin alpha 5 Antibody / ITGA5
RQ5245	NSJ Bioreagents	100ul	EUR 419

anti-Integrin beta 5
YF-PA24023	Abfrontier	50 ul	EUR 400.8
Description: Mouse polyclonal to Integrin beta 5

anti-Integrin beta 5
YF-PA12792	Abfrontier	100 ug	EUR 483.6
Description: Rabbit polyclonal to Integrin beta 5

Rabbit Anti-Human Alpha Defensin 5 (NP-5),antiserum #1
HDEFA51-S	Alpha Diagnostics	100 ul	EUR 548.4

Human Integrin Alpha 5 (ITGa5) ELISA Kit
20-abx151987	Abbexa	EUR 8534.40 EUR 4550.40 EUR 1054.80	10 × 96 tests 5 × 96 tests 96 tests

Human Integrin Alpha 5 (ITGa5) CLIA Kit
20-abx492595	Abbexa	EUR 9567.60 EUR 5095.20 EUR 1177.20	10 × 96 tests 5 × 96 tests 96 tests

Human Integrin Alpha 5 (ITGA5) ELISA Kit
abx571172-96tests	Abbexa	96 tests	EUR 886.8

Human Integrin alpha-5(ITGA5) Elisa kit
CSB-E17350h-24T	Cusabio	1 plate of 24 wells	EUR 198
Description: Quantitativesandwich ELISA kit for measuring Human Integrin alpha-5 (ITGA5) in samples from serum, plasma, cell culture supernates, urine, cerebrospinalfluid (CSF). A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Human Integrin alpha-5(ITGA5) Elisa kit
1-CSB-E17350h	Cusabio	EUR 1080.00 EUR 6571.20 EUR 3480.00	1 plate of 96 wells 10 plates of 96 wells each 5 plates of 96 wells each
Description: Quantitativesandwich ELISA kit for measuring Human Integrin alpha-5(ITGA5) in samples from serum, plasma, cell culture supernates, urine, cerebrospinalfluid(CSF). Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Human Integrin Alpha 5 (ITGa5) ELISA Kit
DLR-ITGa5-Hu-48T	DL Develop	48T	EUR 597.6
Description: A sandwich quantitative ELISA assay kit for detection of Human Integrin Alpha 5 (ITGa5) in samples from tissue homogenates, cell lysates or other biological fluids.

Human Integrin Alpha 5 (ITGa5) ELISA Kit
DLR-ITGa5-Hu-96T	DL Develop	96T	EUR 776.4
Description: A sandwich quantitative ELISA assay kit for detection of Human Integrin Alpha 5 (ITGa5) in samples from tissue homogenates, cell lysates or other biological fluids.

Integrin Alpha 5 (ITGa5) Polyclonal Antibody (Human)
4-PAB287Hu01	Cloud-Clone	EUR 286.80 EUR 2869.20 EUR 717.60 EUR 358.80 EUR 253.20	100ul 10ml 1ml 200ul 20ul
Description: A Rabbit polyclonal antibody against Human Integrin Alpha 5 (ITGa5)

Human ITGA5(Integrin alpha-5) ELISA Kit
EH2445	FN Test	96T	EUR 681.12
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.094 ng/ml

Human ITGA5/ Integrin alpha-5 ELISA Kit
E1342Hu	Sunlong	1 Kit	EUR 726

ELISA kit for Human Integrin alpha-5
EK4913	SAB	96 tests	EUR 804
Description: Enzyme-linked immunosorbent assay kit for quantification of Human Integrin alpha-5 in samples from serum, plasma, tissue homogenates and other biological fluids.

Human Integrin alpha- 5, ITGA5 ELISA KIT
ELI-07691h	Lifescience Market	96 Tests	EUR 988.8

Human Integrin Alpha 5 (ITGa5) ELISA Kit
SEB287Hu-10x96wellstestplate	Cloud-Clone	10x96-wells test plate	EUR 5402.92
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Integrin Alpha 5 (ITGa5) in Tissue homogenates, cell lysates and other biological fluids.

Human Integrin Alpha 5 (ITGa5) ELISA Kit
SEB287Hu-1x48wellstestplate	Cloud-Clone	1x48-wells test plate	EUR 550.13
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Integrin Alpha 5 (ITGa5) in Tissue homogenates, cell lysates and other biological fluids.

Human Integrin Alpha 5 (ITGa5) ELISA Kit
SEB287Hu-1x96wellstestplate	Cloud-Clone	1x96-wells test plate	EUR 734.46
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Integrin Alpha 5 (ITGa5) in Tissue homogenates, cell lysates and other biological fluids.

Human Integrin Alpha 5 (ITGa5) ELISA Kit
4-SEB287Hu	Cloud-Clone	EUR 5463.60 EUR 2886.00 EUR 735.60	10 plates of 96 wells 5 plates of 96 wells 1 plate of 96 wells
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Human Integrin Alpha 5 (ITGa5) in samples from Tissue homogenates, cell lysates and other biological fluids with no significant corss-reactivity with analogues from other species. This is a cost efficient bulk pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits to avoid unsealing the plates and reagents that won't be immediately used.

Human Integrin Alpha 5 (ITGa5) ELISA Kit
SEB287Hu-5x96wellstestplate	Cloud-Clone	5x96-wells test plate	EUR 2945.08
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Integrin Alpha 5 (ITGa5) in Tissue homogenates, cell lysates and other biological fluids.

Human Integrin Alpha 5 (ITGa5) ELISA Kit
RDR-ITGa5-Hu-48Tests	Reddot Biotech	48 Tests	EUR 626.4

Human Integrin Alpha 5 (ITGa5) ELISA Kit
RDR-ITGa5-Hu-96Tests	Reddot Biotech	96 Tests	EUR 868.8

Human Integrin Alpha 5(ITGa5) ELISA Kit
QY-E05294	Qayee Biotechnology	96T	EUR 472.8

Human Integrin Alpha 5 (ITGa5) ELISA Kit
RD-ITGa5-Hu-48Tests	Reddot Biotech	48 Tests	EUR 600

Human Integrin Alpha 5 (ITGa5) ELISA Kit
RD-ITGa5-Hu-96Tests	Reddot Biotech	96 Tests	EUR 830.4

Human Integrin alpha-5(ITGA5) Elisa kit
YLA4349HU-48T	Shanghai YL Biotech	48T	EUR 435

Human Integrin alpha-5(ITGA5) Elisa kit
YLA4349HU-96T	Shanghai YL Biotech	96T	EUR 562.5

Mouse Anti Human Integrin Alpha V Beta 5 Monoclonal Antibody
CABT-49626MH	Creative Diagnostics	0.1 mg	EUR 1650

Anti-alpha 5 beta 1 Integrin (Volociximab), Human IgG4 Antibody
A1092-200	Biovision	each	EUR 874.8

Anti-Integrin alpha antibody
STJ93727	St John's Laboratory	200 µl	EUR 236.4
Description: Rabbit polyclonal to Integrin alpha3.

Anti-Integrin alpha antibody
STJ93728	St John's Laboratory	200 µl	EUR 236.4
Description: Rabbit polyclonal to Integrin alpha4.

Anti-Integrin alpha antibody
STJ93729	St John's Laboratory	200 µl	EUR 236.4
Description: Rabbit polyclonal to Integrin alphaE.

Anti-Integrin alpha antibody
STJ93730	St John's Laboratory	200 µl	EUR 236.4
Description: Rabbit polyclonal to Integrin alphaV.

Anti-Integrin alpha antibody
STJ98181	St John's Laboratory	100 µl	EUR 280.8
Description: Mouse monoclonal to Integrin alpha5.

Anti-Integrin alpha antibody
STJ98510	St John's Laboratory	100 µl	EUR 280.8
Description: Mouse monoclonal to Integrin alpha5.

Anti-Integrin alpha antibody
STJ98511	St John's Laboratory	100 µl	EUR 280.8
Description: Mouse monoclonal to Integrin alpha6.

Anti-Integrin alpha antibody
STJ98709	St John's Laboratory	200 µl	EUR 236.4
Description: Rabbit polyclonal to Integrin alpha1.

Anti-Integrin alpha antibody
STJ98737	St John's Laboratory	200 µl	EUR 236.4
Description: Rabbit polyclonal to Integrin alphaX.

Anti-Integrin alpha antibody
STJ98984	St John's Laboratory	200 µl	EUR 236.4
Description: Rabbit polyclonal to Integrin alphaE.

Anti-Integrin alpha antibody
STJ96613	St John's Laboratory	200 µl	EUR 236.4
Description: Rabbit polyclonal to Integrin alpha4.

Anti-Integrin alpha antibody
STJ96825	St John's Laboratory	200 µl	EUR 236.4
Description: Rabbit polyclonal to Integrin alphaD.

Anti-Integrin alpha antibody
STJ97273	St John's Laboratory	200 µl	EUR 236.4
Description: Rabbit polyclonal to Integrin alphaL.

Anti-Integrin alpha antibody
STJ97283	St John's Laboratory	200 µl	EUR 236.4
Description: Rabbit polyclonal to Integrin alpha2.

Anti-Integrin alpha antibody
STJ97284	St John's Laboratory	200 µl	EUR 236.4
Description: Integrin alpha5 is a protein encoded by the ITGA5 gene which is approximately 114,5 kDa. Integrin alpha5 is localised to the cell membrane and is involved in the MAPK-Erk pathway, apoptotic pathways, integrin pathway, focal adhesion and blood-brain barrier and immune cell transmigration. Integrins are heterodimeric integral membrane proteins composed of an alpha subunit and a beta subunit that function in cell surface adhesion and signalling. Integrin alpha5 is expressed in the liver, lung, nervous system, bone marrow and blood. Mutations in the ITGA5 gene may result in colon carcinoma and congenital epulis STJ97284 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of Integrin alpha5 protein.

Anti-Integrin alpha antibody
STJ97285	St John's Laboratory	200 µl	EUR 236.4
Description: Rabbit polyclonal to Integrin alpha6.

Anti-Integrin alpha antibody
STJ97657	St John's Laboratory	200 µl	EUR 236.4
Description: Rabbit polyclonal to Integrin alpha3.

anti-Integrin alpha 6
YF-PA24004	Abfrontier	50 ul	EUR 400.8
Description: Mouse polyclonal to Integrin alpha 6

anti-Integrin alpha 1
YF-PA24011	Abfrontier	50 ul	EUR 400.8
Description: Mouse polyclonal to Integrin alpha 1

anti-Integrin alpha 4
YF-PA24013	Abfrontier	50 ul	EUR 400.8
Description: Mouse polyclonal to Integrin alpha 4

anti-Integrin alpha 9
YF-PA24015	Abfrontier	50 ul	EUR 400.8
Description: Mouse polyclonal to Integrin alpha 9

anti-Integrin alpha E
YF-PA24017	Abfrontier	50 ul	EUR 400.8
Description: Mouse polyclonal to Integrin alpha E

anti-Integrin alpha 6
YF-PA12761	Abfrontier	50 ul	EUR 435.6
Description: Mouse polyclonal to Integrin alpha 6

anti-Integrin alpha 6
YF-PA12762	Abfrontier	100 ug	EUR 483.6
Description: Rabbit polyclonal to Integrin alpha 6

anti-Integrin alpha 1
YF-PA12784	Abfrontier	50 ug	EUR 435.6
Description: Mouse polyclonal to Integrin alpha 1

anti-Integrin alpha 4
YF-PA12785	Abfrontier	100 ug	EUR 483.6
Description: Rabbit polyclonal to Integrin alpha 4

anti-Integrin alpha V
YF-PA12786	Abfrontier	50 ul	EUR 435.6
Description: Mouse polyclonal to Integrin alpha V

anti-Integrin alpha V
YF-PA12787	Abfrontier	50 ug	EUR 435.6
Description: Mouse polyclonal to Integrin alpha V

anti-Integrin alpha V
YF-PA12788	Abfrontier	100 ug	EUR 483.6
Description: Rabbit polyclonal to Integrin alpha V

Mouse Integrin Alpha 5 (ITGa5) Protein
20-abx168338	Abbexa	EUR 794.40 EUR 326.40 EUR 2448.00 EUR 944.40 EUR 577.20	100 ug 10 ug 1 mg 200 ug 50 ug

Cow Integrin Alpha 5 (ITGa5) Protein
20-abx067274	Abbexa	EUR 927.60 EUR 360.00 EUR 2932.80 EUR 1111.20 EUR 661.20	100 ug 10 ug 1 mg 200 ug 50 ug

Integrin alpha 5 recombinant monoclonal antibody
A5201	Bimake	100ul X 3	EUR 714
Description: A recombinant monoclonal antibody from rabbit against human Integrin alpha 5 for WB,ELISA

Integrin Alpha 5 (ITGA5) Antibody (HRP)
20-abx336126	Abbexa	EUR 493.20 EUR 2214.00 EUR 718.80 EUR 218.40 EUR 360.00	100 ug 1 mg 200 ug 20 ug 50 ug

Integrin Alpha 5 (ITGA5) Antibody (FITC)
20-abx336127	Abbexa	EUR 493.20 EUR 2214.00 EUR 718.80 EUR 218.40 EUR 360.00	100 ug 1 mg 200 ug 20 ug 50 ug

Integrin Alpha 5 (ITGA5) Antibody (Biotin)
20-abx336128	Abbexa	EUR 493.20 EUR 2214.00 EUR 718.80 EUR 218.40 EUR 360.00	100 ug 1 mg 200 ug 20 ug 50 ug

Integrin Alpha 5 (ITGA5) Antibody (FITC)
abx413989-01mg	Abbexa	0.1 mg	EUR 610.8

Integrin alpha 5 (CD49e) Blocking Peptide
AF5200-BP	Affbiotech	1mg	EUR 234

Rabbit Anti-Human Alpha Defensin 5 (NP-5),, IgG #1, aff pure
HDEFA51-A	Alpha Diagnostics	100 ug	EUR 578.4

Anti-Integrin beta-5 antibody
PAab04352	Lifescience Market	100 ug	EUR 426

anti- Integrin beta-5 antibody
FNab04352	FN Test	100µg	EUR 606.3
Description: Antibody raised against Integrin beta-5

Anti-Integrin beta 5 antibody
STJ70659	St John's Laboratory	100 µg	EUR 430.8

Anti-Integrin beta 5 (1D8)
YF-MA13874	Abfrontier	100 ug	EUR 435.6
Description: Mouse monoclonal to Integrin beta 5

Anti-Integrin ß-5 Antibody
A1832-100	Biovision	each	EUR 418.8

Anti-Integrin ß-5 Antibody
A1832-30T	Biovision	each	EUR 175.2

Integrin Alpha 5 (ITGa5) Polyclonal Antibody (Human), APC
4-PAB287Hu01-APC	Cloud-Clone	EUR 399.60 EUR 3735.60 EUR 1046.40 EUR 507.60 EUR 258.00	100ul 10ml 1ml 200ul 20ul
Description: A Rabbit polyclonal antibody against Human Integrin Alpha 5 (ITGa5). This antibody is labeled with APC.

Integrin Alpha 5 (ITGa5) Polyclonal Antibody (Human), Biotinylated
4-PAB287Hu01-Biotin	Cloud-Clone	EUR 363.60 EUR 2809.20 EUR 836.40 EUR 442.80 EUR 259.20	100ul 10ml 1ml 200ul 20ul
Description: A Rabbit polyclonal antibody against Human Integrin Alpha 5 (ITGa5). This antibody is labeled with Biotin.

Integrin Alpha 5 (ITGa5) Polyclonal Antibody (Human), Cy3
4-PAB287Hu01-Cy3	Cloud-Clone	EUR 483.60 EUR 4930.80 EUR 1345.20 EUR 627.60 EUR 294.00	100ul 10ml 1ml 200ul 20ul
Description: A Rabbit polyclonal antibody against Human Integrin Alpha 5 (ITGa5). This antibody is labeled with Cy3.

Integrin Alpha 5 (ITGa5) Polyclonal Antibody (Human), FITC
4-PAB287Hu01-FITC	Cloud-Clone	EUR 344.40 EUR 3012.00 EUR 860.40 EUR 430.80 EUR 230.40	100ul 10ml 1ml 200ul 20ul
Description: A Rabbit polyclonal antibody against Human Integrin Alpha 5 (ITGa5). This antibody is labeled with FITC.

Integrin Alpha 5 (ITGa5) Polyclonal Antibody (Human), HRP
4-PAB287Hu01-HRP	Cloud-Clone	EUR 366.00 EUR 3256.80 EUR 926.40 EUR 459.60 EUR 243.60	100ul 10ml 1ml 200ul 20ul
Description: A Rabbit polyclonal antibody against Human Integrin Alpha 5 (ITGa5). This antibody is labeled with HRP.

Integrin Alpha 5 (ITGa5) Polyclonal Antibody (Human), PE
4-PAB287Hu01-PE	Cloud-Clone	EUR 344.40 EUR 3012.00 EUR 860.40 EUR 430.80 EUR 230.40	100ul 10ml 1ml 200ul 20ul
Description: A Rabbit polyclonal antibody against Human Integrin Alpha 5 (ITGa5). This antibody is labeled with PE.

ELISA kit for Human ITGa5 (Integrin Alpha 5)
ELK3746	ELK Biotech	1 plate of 96 wells	EUR 518.4
Description: A sandwich ELISA kit for detection of Integrin Alpha 5 from Human in samples from blood, serum, plasma, cell culture fluid and other biological fluids.

Recombinant Antibody to Integrin Alpha 5 (ITGa5) (Human)
4-RAB287Hu21	Cloud-Clone	EUR 406.80 EUR 4754.40 EUR 1146.00 EUR 530.40 EUR 303.60	100ul 10ml 1ml 200ul 20ul
Description: A Recombinant antibody against Human Integrin Alpha 5 (ITGa5)

Rabbit Polyclonal antibody Anti-CRBN
Anti-CRBN	ImmunoStep	50 µg	EUR 418.8

Cow Integrin Alpha 5 (ITGA5) ELISA Kit
abx521007-96tests	Abbexa	96 tests	EUR 1093.2

Mouse Integrin Alpha 5 (ITGA5) ELISA Kit
abx521009-96tests	Abbexa	96 tests	EUR 886.8

Integrin Alpha 5 (ITGa5) Polyclonal Antibody (Bovine)
4-PAB287Bo01	Cloud-Clone	EUR 320.40 EUR 3391.20 EUR 836.40 EUR 405.60 EUR 266.40	100ul 10ml 1ml 200ul 20ul
Description: A Rabbit polyclonal antibody against Bovine Integrin Alpha 5 (ITGa5)

Integrin Alpha 5 (ITGa5) Polyclonal Antibody (Mouse)
4-PAB287Mu01	Cloud-Clone	EUR 291.60 EUR 2948.40 EUR 735.60 EUR 366.00 EUR 254.40	100ul 10ml 1ml 200ul 20ul
Description: A Rabbit polyclonal antibody against Mouse Integrin Alpha 5 (ITGa5)

ELISA kit for Mouse Integrin alpha-5
EK4914	SAB	96 tests	EUR 804
Description: Enzyme-linked immunosorbent assay kit for quantification of Mouse Integrin alpha-5 in samples from serum, plasma, tissue homogenates and other biological fluids.

Mouse Itga5/ Integrin alpha-5 ELISA Kit
E0812Mo	Sunlong	1 Kit	EUR 758.4

Mouse Integrin alpha- 5, Itga5 ELISA KIT
ELI-07692m	Lifescience Market	96 Tests	EUR 1038

Bovine Integrin alpha- 5, ITGA5 ELISA KIT
ELI-07693b	Lifescience Market	96 Tests	EUR 1113.6

Anti-Integrin alpha-1 antibody
PAab04343	Lifescience Market	100 ug	EUR 494.4

Anti-Integrin alpha-3 antibody
PAab04344	Lifescience Market	100 ug	EUR 494.4

Anti-Integrin alpha-4 antibody
PAab04346	Lifescience Market	100 ug	EUR 426

Anti-Integrin alpha-9 antibody
PAab04348	Lifescience Market	100 ug	EUR 426

anti- Integrin alpha-1 antibody
FNab04343	FN Test	100µg	EUR 702
Description: Antibody raised against Integrin alpha-1

anti- Integrin alpha-3 antibody
FNab04344	FN Test	100µg	EUR 702
Description: Antibody raised against Integrin alpha-3

anti- Integrin alpha-3 antibody
FNab04345	FN Test	100µg	EUR 702
Description: Antibody raised against Integrin alpha-3

anti- Integrin alpha-4 antibody
FNab04346	FN Test	100µg	EUR 606.3
Description: Antibody raised against Integrin alpha-4

anti- Integrin alpha-9 antibody
FNab04348	FN Test	100µg	EUR 606.3
Description: Antibody raised against Integrin alpha-9

Anti-Integrin alpha 6 (4C1)
YF-MA13842	Abfrontier	100 ug	EUR 435.6
Description: Mouse monoclonal to Integrin alpha 6

Anti-Integrin alpha 1 (4G11)
YF-MA13866	Abfrontier	100 ug	EUR 435.6
Description: Mouse monoclonal to Integrin alpha 1

Anti-Integrin alpha 4 (2G10)
YF-MA13867	Abfrontier	100 ug	EUR 435.6
Description: Mouse monoclonal to Integrin alpha 4

Anti-Integrin alpha 9 (3E4)
YF-MA13869	Abfrontier	100 ug	EUR 435.6
Description: Mouse monoclonal to Integrin alpha 9

Anti-Integrin alpha E (6B8)
YF-MA13870	Abfrontier	100 ug	EUR 435.6
Description: Mouse monoclonal to Integrin alpha E

Anti-Integrin alpha 4 (2C11)
YF-MA10493	Abfrontier	100 ug	EUR 435.6
Description: Mouse monoclonal to Integrin alpha 4

Integrin Alpha 5 (ITGa5) Polyclonal Antibody (Human), APC-Cy7
4-PAB287Hu01-APC-Cy7	Cloud-Clone	EUR 656.40 EUR 7327.20 EUR 1948.80 EUR 872.40 EUR 372.00	100ul 10ml 1ml 200ul 20ul
Description: A Rabbit polyclonal antibody against Human Integrin Alpha 5 (ITGa5). This antibody is labeled with APC-Cy7.

Recombinant Antibody to Integrin Alpha 5 (ITGa5) (Human), APC
4-RAB287Hu21-APC	Cloud-Clone	EUR 580.80 EUR 6306.00 EUR 1688.40 EUR 765.60 EUR 333.60	100ul 10ml 1ml 200ul 20ul
Description: A Recombinant antibody against Human Integrin Alpha 5 (ITGa5). This antibody is labeled with APC.

Recombinant Antibody to Integrin Alpha 5 (ITGa5) (Human), Biotinylated
4-RAB287Hu21-Biotin	Cloud-Clone	EUR 495.60 EUR 4694.40 EUR 1308.00 EUR 631.20 EUR 314.40	100ul 10ml 1ml 200ul 20ul
Description: A Recombinant antibody against Human Integrin Alpha 5 (ITGa5). This antibody is labeled with Biotin.